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27,384 recruiting studies available now

A Pilot Study of Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis

Background: Chronic granulomatous disease (CGD) weakens the body's defense against germs. CGD can also damage the colon. It can cause inflammation (colitis) t…

Chronic Granulomatous Disease-associated Colitis

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT05333471

Observational

Exploring Water-free Sodium Storage

The overarching goal of this proposal is to definitively establish if acute water free Na storage and release occurs, if the amount stored/released is of a qua…

Peritoneal Dialysis, Heart Failure

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT06872645

Phase 3

Phase 3, Double-blind, Placebo-controlled, Multicentre Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

The primary objective of this study is to evaluate the efficacy of two different doses of Atenativ, versus placebo, in restoring and maintaining heparin respon…

Acquired Antithrombin Deficiency

Estimated

~$50 – $2,100

Actual pay is set by the research site.

OctapharmaNCT06096116

Phase 2

Efficacy and Safety of PUL-042 Inhalation Solution in Reducing Lower Respiratory Tract Complications in Patients With Hematologic Malignancies and Recipients of Hematopoietic Stem Cell Transplantation (HSCT) With Documented Viral Infections With PIV, hMPV or RSV

The purpose of this research study is to try to see whether an experimental drug, PUL 042 Inhalation Solution (PUL 042), is effective in reducing the severity …

Hematologic MalignanciesHematopoietic Stem Cell Transplant (HSCT)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Pulmotect, Inc.NCT06665100

Phase 2

A Phase II Study of Combined Amivantamab, Carboplatin and Paclitaxel in Unresectable Locally Recurrent or Metastatic Head and Neck Cancer

This research study is for people who have head and neck cancer that has come back or spread to other places in the body.

Head &Amp; Neck CancerHead &Amp; Neck Squamous Cell Carcinoma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

SWOG Cancer Research NetworkNCT07062354

Observational

Deep Brain Stimulation of the Motor Thalamus Combined With Speech and Swallowing Therapy to Improve Post-Stroke Motor Speech and Swallowing Production Impairments

The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabi…

StrokeDysarthriaApraxia+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Pirondini, Elvira, PhDNCT07849114

The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older Adults (Depression and Driving)

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

DepressionDrive

Estimated

~$10 – $750

Actual pay is set by the research site.

Washington University School of MedicineNCT05446805

Phase 4

Neurovascular Effects of Empagliflozin in Mid-Life and Older Adults With Prehypertension

The goal of this clinical trial is to examine whether empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, improves vascular and autonomic funct…

Blood PressureEndothelial Dysfunction

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Kanokwan BunsawatNCT07799441

Observational

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

This study plans to learn more about how different types of snacks may affect brain processes relating to eating behaviors during a diet intervention.

Overweight/Obesity

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Colorado, DenverNCT07428187

Viability Assessment Using Flavin Mononucleotide (FMN) Measured in Perfusate and Bile During Normothermic Machine Perfusion: an International, Multi-center Validation Study

Discarded perfusate samples will be collected from donors after circulatory death (DCD) or donors after brain death (DBD) organs during the machine perfusion p…

Liver Transplant Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

The Cleveland ClinicNCT07315204

Phase 1

Xylitol Use for Decolonization of C. Difficile in Patients With Inflammatory Bowel Disease

This is a randomized, placebo-controlled, dose-ranging study to assess the safety and efficacy of xylitol as an oral therapeutic for decolonization of C. diffi…

Inflammatory Bowel DiseasesClostridioides Difficile Infection

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Brigham and Women's HospitalNCT05852587

Phase 1

Influence of Orexin Antagonism on Motivation for Alcohol

This research will translate findings from preclinical research and provide the initial clinical evidence that orexin antagonism reduces motivation for alcohol…

Alcohol Use Disorder

Estimated

~$500 – $11,250

Actual pay is set by the research site.

William StoopsNCT06326684