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27,354 recruiting studies available now

Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study

This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a …

StrokeStroke, ChronicFatigue

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT05584124

Phase 2

A Phase 2, Multicenter, Double-Blind, Randomized, Controlled Trial of the Safety and Immunogenicity of a Self-Amplifying mRNA COVID-19 Vaccine in Adult Hematopoietic Cell Transplant Recipients

This phase IIb trial compares the effect of LUNAR-COV19 vaccine to Comirnaty vaccine in treating adult patients who have received a hematopoietic cell transpla…

Hematopoietic and Lymphatic System Neoplasm

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT07390968

Phase 1

Open-Label, Cohort-Sequential Dose-Escalation and Dose-Confirmation Phase 1/2 Clinical Trial to Evaluate the Safety and Efficacy of Domatinostat in Combination With Sirolimus in Adolescents and Adults With Relapsed, Refractory Sarcoma and Osteosarcoma

This is a multicenter, open-label, Phase 1/2 study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of domatinos…

SarcomaOsteosarcoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

H. Lee Moffitt Cancer Center and Research InstituteNCT07725380

Observational

Pivotal TRIal to Evaluate TraNsvenous TrIcuspid Valve ReplacemenT With Lux Valve Plus System in Patients With Severe or Greater Tricuspid Regurgitation - Clinical SafetY and Effectiveness

The goal of this clinical trial is to learn if LuX-Valve Plus system works to treat symptomatic subjects with at least severe tricuspid regurgitation (TR). It …

Tricuspid Regurgitation (TR)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Jenscare Innovation Inc.NCT07454980

Pediatric Cardiomyopathy Mutation Analysis

The goal of this protocol is to obtain information from individuals with cardiomyopathy and from their families in order to elucidate the molecular genetics of…

CardiomyopathiesDilated CardiomyopathyHypertrophic Cardiomyopathy+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT02432092

Phase 1

IIT2021-12-Reckamp-Osi105: Phase I Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

The purpose of this study is to examine the combination of osimertinib and carotuximab to assess the safety and find the recommended dose for treatment of adva…

Non Small Cell Lung CancerLung Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Karen Reckamp, MD, MSNCT05401110

Observational

A Feasibility Clinical Trial of Exablate for Low Intensity Focused Ultrasound Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Abuse Disorders (SUDs)

The purpose of this clinical trial is to investigate Low Intensity Focused Ultrasound (LIFU) using the Exablate® Model 4000 Type 2.0/2.1 as an adjunctive neuro…

Opioid-use DisorderSubstance Use Disorders

Estimated

~$10 – $1,125

Actual pay is set by the research site.

InSightecNCT04197921

Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure

This a single-center, retrospective, observational study of patients that undergo coronary sinus(CS) lead revision, comparing epicardial lead placement to coro…

Heart Failure With Reduced Ejection Fraction

Estimated

~$10 – $750

Actual pay is set by the research site.

Kansas City Heart Rhythm Research FoundationNCT06342492

Modeling Adherence to Preventive Swallowing Exercises in Head and Neck Cancer

This trial uses blood tests and questionnaires to study how well participants with head and neck cancer that has spread to other places in the body adhere to s…

Carcinoma of Unknown PrimaryClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+28 more

Phase 1

Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

Hypoxic-Ischemic Encephalopathy (HIE) occurs in 20 per 1000 births. Only 47% of neonates treated with the state of the art therapy (induced systemic hypothermi…

Hypoxic Ischemic Encephalopathy

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of FloridaNCT02621944

Observational

Effect of Acute Intermittent Hypoxia in Healthy Individuals

The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and syn…

Healthy

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Shirley Ryan AbilityLabNCT04691518

Phase 1

A Study Evaluating Escalating Doses of 211^At-Labeled Anti-CD45 MAb BC8-B10 (211^At-BC8-B10) Followed by Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), or Myelodysplastic Syndrome (MDS)

This phase I/II trial studies the side effects and best dose of 211\^astatine(At)-BC8-B10 before donor stem cell transplant in treating patients with high-risk…

Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia+9 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.