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A Phase 2a, Multi-Center, Randomized, Open-Label Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 Administered by Endoscopic Ultrasound-Guided Peripancreatic Injection Plus Standard-of-Care Versus Standard-of-Care Only in Participants With Predicted Severe Acute Pancreatitis

The goal of this clinical trial is to test the safety and effectiveness of a single dose of RABI-767 given by endoscopic ultrasound (EUS) guided peripancreatic…

Acute Pancreatitis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Panafina, Inc.NCT06080789

Phase 1

A Multiple-Center Study to Evaluate the Skin Irritation and Sensitization Potential of a Test Estradiol/Levonorgestrel Transdermal Delivery System (Corium TDS)

The two products used in this study are transdermal patches that contain selegiline. The test drug is the Estradiol/Levonorgestrel Transdermal Delivery System …

MenopauseHealthy Female Participants

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Corium Innovations, Inc.NCT07794150

Observational

Feasibility Study of a Brief Intervention to Support Medication Collaboration Among Older Adults and Family Care Partners

This study examines the feasibility and acceptability of a brief medication collaboration intervention among older adults (age 60+) with early-stage dementia o…

Dementia Family CaregiverDementiaMedication Adherence

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT07742189

Observational

Ifluence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effect

To explore consumer responses to the announcement and implementation of new modified risk claims for Copenhagen and General Snus (brands of smokeless tobacco (…

Smoking Behaviors

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Roswell Park Cancer InstituteNCT07102082

Observational

Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions

It is a 12-week study. The participants will follow three different diets, and during each diet period, and the participants will wear our device, and blood sa…

NAFLD (Nonalcoholic Fatty Liver Disease)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

VA Greater Los Angeles Healthcare SystemNCT06932289

Phase 1

A Phase 1/1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

The purpose of this first-in-human study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AMG…

KRAS Altered Advanced or Metastatic Solid Tumors

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AmgenNCT07094113

Phase 3

Lumateperone for Late-Life Depression

The purpose of this research study is to examine how well a medication called lumateperone (Caplyta) works to relieve depression in older adults with treatment…

Treatment Resistant Depression (TRD)Late Life Depression (LLD)Depression / Major Depressive Disorder

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Eric LenzeNCT07623135

Observational

Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On: Project 2 - Producing Outcome Measures for OTP Quality Improvement

This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet m…

Opioid Use Disorder

Estimated

~$10 – $1,125

Actual pay is set by the research site.

RTI InternationalNCT07214389

Recovery Trajectory for Coma and Disorders of Consciousness

This study aims to better understand recovery after coma caused by serious neurologic illness or injury. Patients who are unconscious (in a coma or disorder of…

ComaDisorders of ConsciousnessCardiac Arrest (CA)+5 more

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT07614074

Phase 1

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

To find a recommended dose of the combination of alpelisib and pembrolizumab that can be given to patients with metastatic breast cancer or melanoma.

Melanoma (Skin Cancer)Breast CancerBrain Metastasases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT06545682

Observational

A Prospective Randomized Study Comparing Positive Language vs Common Language During Inhalational Induction

The aim of this study is to compare the impact of common (standard of care) language vs positive language used by clinicians during inhalational induction of a…

Emergence DeliriumAnesthesia; Adverse Effect

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT06324955

Observational

Effects of Fresh Mango as a Table Sugar Replacement on Postprandial Intestinal Permeability and Inflammation Following a High-Sugar Breakfast.

Systemic inflammation and intestinal hyperpermeability (disruption of the gut barrier which allows nutrient molecules and bacteria to enter the bloodstream) ar…

Healthy Participants

Estimated

~$10 – $750

Actual pay is set by the research site.

Ball State UniversityNCT07650058