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27,293 recruiting studies available now

Therapeutic RSK1 Targeting in Myeloid Malignancies

This study hypothesizes that PMD-026, an oral inhibitor of ribosomal protein S6 kinase A1 (RSK1), is safe and well tolerated in participants with myelofibrosis…

Myeloid Malignancy

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Washington University School of MedicineNCT07379125

Observational

Tear Fluid Collection in Patients Before and After Corneal Incision or Trauma.

Tear fluid will be collected from patients diagnosed with ocular trauma at the University of Pittsburgh Medical Center to evaluate biomarkers.

Ocular Trauma

Estimated

~$10 – $1,050

Actual pay is set by the research site.

InnSight Technology, Inc.NCT07887425

Phase 1

A PHASE 1/2A STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTI-TUMOR ACTIVITY OF PF-07220060 AS A SINGLE AGENT AND AS PART OF COMBINATION THERAPY IN PARTICIPANTS WITH ADVANCED SOLID TUMORS

This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 adm…

LiposarcomaProstate CancerAdvanced Breast Cancer+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

PfizerNCT04557449

Observational

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

The primary purpose of this research study is to determine if forces within carbon fiber custom dynamic orthoses (CDOs) can be reliability assessed using Loadp…

HealthyAnkle Foot Orthosis (AFO)Peripheral Neuropathy

Estimated

~$10 – $750

Actual pay is set by the research site.

University of IowaNCT06127264

Observational

Sleep Promoting Intervention to Improve Diabetes Outcomes and Executive Function in Adolescents With T1D

The goal of this work is to conduct a randomized trial evaluating the effects of a behavioral intervention to increase sleep duration and quality for adolescen…

Type 1 Diabetes

Estimated

~$10 – $750

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT06516614

Prospective Clinical Evaluation of Circulating Tumor DNA Liquid Biopsy and Spectroscopy-based Molecular Urinalysis in Patients With Sarcoma

The purpose of this research study is to see how well Low Pass Whole Genome Sequencing (LP-WGS) can detect circulating tumor deoxyribonucleic acid (ctDNA) in t…

Sarcoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT06958107

Phase 1

IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

This Phase 1, multicenter, open-label trial will assess the safety and feasibility of IFx-Hu2.0 as adjunctive therapy to pembrolizumab in adult participant (≥1…

Advanced Or Metastatic Merkel Cell Carcinoma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

TuHURA Biosciences, Inc.NCT06940440

Observational

INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study

Neurological DisorderALS (Amyotrophic Lateral Sclerosis)Motor Neuron Disease+2 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Synchron, Inc.NCT07543367

Observational

A Randomized Intervention Trial to Increase Access to Reproductive Health Services Among Adolescents and Young Adults With Intellectual and Developmental Disabilities

The goal of this clinical trial is to test the effectiveness of a 6-week socialization and sex education curriculum (STEPS2) in young people (aged 16-27 years)…

KnowledgeBehavior

Estimated

~$10 – $675

Actual pay is set by the research site.

City University of New York, School of Public HealthNCT06231485

Phase 3

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

This study is an open-label, randomized, multicenter trial that incorporates a multi-arm design comparing each of 3 non-TNFi (Tumor Necrosis Factor inhibitor) …

Polyarticular Course Juvenile Idiopathic Arthritis (JIA)

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Duke UniversityNCT06654882

Phase 2

A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults With Cutaneous Sarcoidosis

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis.

Cutaneous Sarcoidosis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Priovant Therapeutics, Inc.NCT06978725

Observational

The Management of Necrotizing Soft Tissue Infection Wounds With Cytal® Wound Matrix and MicroMatrix®

This is a prospective, pilot, parallel group, randomized controlled trial with 1:1 allocation. This will be a single center study coordinated at the Cleveland …

Necrotizing FascitisNecrotizing Soft Tissue Infection

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Benjamin T. MillerNCT06857708