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3,226 recruiting studies matching your filters

Phase II Study of Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer

Advanced cervical cancer patients treated with standard of care (SOC) chemoradiation plus glutaminase inhibition with telaglenastat (CB-839) will have increase…

Advanced Cervical CarcinomaCervical CancerCervix Cancer+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Washington University School of MedicineNCT05521997

Phase 1

GUARDIAN-101: A Phase 1 Dose Escalation and Expansion Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Phase 1 dose escalation and expansion study of CLSP-1025, a first-in-class HLA-A\*02:01 specific T cell engager (TCE) targeting solid tumors that harbor the p5…

Advanced Solid TumorUnresectable Solid TumorMetastatic Solid Tumor+8 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Clasp Therapeutics, Inc.NCT06778863

Phase 4

Indomethacin vs. no Indomethacin for Patients Undergoing Biliary ERCP With Prior Biliary Sphincterotomy

This study is a randomized clinical trial evaluating the efficacy of rectal indomethacin in preventing post-endoscopic retrograde cholangiopancreatography (ERC…

Pancreatitis BiliaryPancreatitis Acute BiliaryPancreatitis+3 more

Estimated

~$25 – $900

Actual pay is set by the research site.

University of California, San FranciscoNCT07661498

Phase 3

A Phase 3, Multi-Center, Randomized, Open-Label Clinical Study of Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy as First-Line Treatment in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

This study is designed to assess the levels of drug exposure following treatment with tislelizumab administered as a subcutaneous (SC) injection compared to in…

Metastatic Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

BeOne MedicinesNCT07043400

Phase 1

Phase I Trial of [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers

Background: Some cancers have high levels of proteins called somatostatin receptors (SSTRs) on the surface of the tumors. These tumors can be in the lung, hea…

Sinonasal Neuroendocrine CarcinomaNasopharyngeal CarcinomaEsthesioneuroblastoma+7 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)

Observational

Cardiac Point-of-care Ultrasound Clinical Training Pathway Implementation and Impact Assessment for Advanced Practice Providers in the Emergency Department

The aim of this study is to assess emergency medicine physician and advanced practice provider (APP) knowledge and technical skill in performance of a point-of…

Cardiovascular Disease AcuteEmergency Department PatientHeart Failure Acute+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT07159269

Phase 2

Phase 2 Study of Avapritinib in Patients With CKIT or PDGFRA Mutation-Positive Malignant Solid Tumors

This phase II trial studies the effect of avapritinib in treating malignant solid tumors that have a genetic change (mutation) in CKIT or PDGFRA and have sprea…

Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26 more

Phase 1

A Phase 1, Single Ascending Dose Administration of MIB-725 to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Community Dwelling Healthy Adults

This is a single center, open label (i.e. participants and study staff will not be masked to the intervention) single ascending dose study to evaluate the safe…

Healthy Adults

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Metro International Biotech, LLCNCT06815991

Observational

Prospective Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and Neck

The purpose of this study would like to learn if acupuncture-like electrical therapy can be used in patients with head and neck cancer who have had radiation t…

Head and Neck Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of RochesterNCT04805528

Phase 2

An Open-Label, Phase 2 Study of NEO100 in Participants With Residual, Progressive or Recurrent High-Grade Meningioma

This multi-site, Phase 2 clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen of NEO100 (per…

Residual, Progressive or Recurrent Grade II or III Meningioma

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Neonc Technologies, Inc.NCT05023018

A Prospective Study To Define The Role Of Various Factors In Development And Progression Of Gastroesophageal Reflux Disease (GERD) And Barrett's Esophagus And The Creation Of A Registry.

The purpose of this study is to determine or evaluate the risk factors such as smoking, family history etc. that cause esophageal cancer and to determine the g…

Barrett's EsophagusGastroesophageal Reflux DiseaseEsophageal Adenocarcinoma

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Midwest Biomedical ResearchNCT00574327

Evaluating the Role of the Microbiome in Antidepressant Treatment in Adolescents.

The goal of this observational study is to learn about the role of the human gut microbiome in antidepressant treatment response in adolescents with Major Depr…

Depression in Adolescence

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, San DiegoNCT06633497