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3,219 recruiting studies matching your filters

A Multi-center Phase II Study of Combining Cabozantinib and Atezolizumab as the 1st Line Therapy for PD-L1 Negative Advanced/Metastatic NSCLC (Cabatezo-1)

NSCLC patients with low expression level of PD-L1, esp. those with its level less than 1%, do not derive much benefit from anti-PD-1/L1 therapy (e.g. atezoilzu…

Lung CancerNSCLC Stage IVMetastatic NSCLC - Non-Small Cell Lung Cancer+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Jun Zhang, MD, PhDNCT05859217

Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy

This trial aims at investigating the diagnostic ability of a combined diagnostic panel including systematic endoscopic evaluation (SEE), blood-based ctDNA assa…

Urothelial CarcinomaMuscle Invasive Bladder Urothelial CarcinomaNon-Muscle Invasive Bladder Urothelial Carcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Fox Chase Cancer CenterNCT06396533

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 followi…

LVADFrailtyGI Bleed+5 more

Estimated

~$10 – $750

Actual pay is set by the research site.

International Consortium of Circulatory Assist CliniciansNCT06039176

Sleep Health in the Rural South and Its Relationships With Cardiometabolic Health Disparities

Rural communities in the southern U.S. suffer a disproportionate burden of morbidity and mortality from cardiometabolic disease, with traditional risk factors …

Sleep ApneaInsomniaSleep Deprivation+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT06336525

Observational

Adverse Adolescent Pathways to Substance Use

Purpose: This 5-year R01 study will elucidate the role of maturational change across adolescence in neural connectivity and physiological stress responses in t…

AnxietyAdolescent DevelopmentSubstance Use

Estimated

~$10 – $750

Actual pay is set by the research site.

University of North Carolina, Chapel HillNCT06977178

Use of Viscoelastic Assays Beyond Coagulation: Pre- and Post-operative TEG

The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and…

Liver CancerEsophageal CancerColorectal Cancer+4 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Colorado, DenverNCT05517811

Observational

Effects of Remote Ischemic Conditioning Combined With Motor Training on Spinal Reflex Modulation in Healthy Young Adults

Remote ischemic conditioning (RIC) is a clinically feasible method that protects distant organs from severe injury through brief, sub lethal periods of ischemi…

Healthy Young Adults

Estimated

~$10 – $750

Actual pay is set by the research site.

East Carolina UniversityNCT06860464

Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer

Through this study, we hope to learn more about the mechanisms, which may contribute to development and progression of head and neck cancer. The long-term goal…

Head and Neck Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT00230308

Phase 1

A Phase 1A/B Study To Evaluate The Safety And Tolerability Of EBC-129 As A Single Agent And In Combination With Pembrolizumab In Advanced Solid Tumours

This study will assess the safety and tolerability of EBC-129 as a single agent and in combination with pembrolizumab in patients with advanced solid tumours

Advanced Solid Tumours

Estimated

~$150 – $4,500

Actual pay is set by the research site.

EDDC (Experimental Drug Development Centre), A*STAR Research EntitiesNCT05701527

A Multi-Modal Wearable Sensor for Early Detection of Cognitive Decline and Remote Monitoring of Cognitive-Motor Decline Over Time

This observational study will enroll approximately 100 participants evenly split by cognitive status (Cognitively Impaired vs Non-Cognitively Impaired), and in…

Mild Cognitive Impairment (MCI)Older Adults With Cognitive DeclineOlder Adults

Estimated

~$10 – $1,125

Actual pay is set by the research site.

BioSensicsNCT07780162

Observational

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-CA, to improve the quality of life and cognitive function in Servi…

Brain CancerBrain TumorBrain Neoplasms+9 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Dartmouth-Hitchcock Medical CenterNCT06930846

Phase 2

Systems Biology of a mRNA Vaccine Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Given Via Intradermal (ID) Injection Using Tropis Needle-Free Injection System (NFIS) or Intramuscular (IM) Injection Using Needle and Syringe

The purpose of this study is to determine if immune responses differ when the mRNA COVID-19 vaccine is given through different delivery methods, including a ne…

Evaluate Immune Responses Following mRNA COVID-19 Vaccine Administration Through Different Delivery Routes in Healthy VolunteersSARS CoV-2

Estimated

~$75 – $2,800

Actual pay is set by the research site.

PharmaJet, Inc.NCT06919796