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335 recruiting studies matching your filters

Intravesical Lactobacillus rhamnosusGG Versus Saline Bladder Wash: A Randomized, Controlled, Comparative Effectiveness Clinical Trial

This is the first ever comparative effectiveness study of an antibiotic-sparing novel self-management intervention to prevent complicated urinary tract infecti…

Spinal Cord InjuriesNeurogenic Bladder

Estimated

~$10 – $7,500

Medstar Health Research InstituteNCT05230511

Phase 2

Adjuvant Sacituzumab Govitecan Plus Nivolumab in Patients With Muscle-Invasive Urothelial Carcinoma at High-Risk for Recurrence

This is a phase 2 study, single-arm study of adjuvant combination therapy with Sacituzumab Govitecan and Nivolumab in patients with muscle-invasive urothelial …

Urothelial CarcinomaMuscle-invasive Bladder Cancer

Estimated

~$10 – $6,250

University of California, IrvineNCT06682728

Observational

Robotic Vascularized Composite Bladder Allograft Transplantation: A Phase 0 (First-in-Human), Single Institutional Study for Deceased-Donor Bladder Transplantation

This phase 0 trial tests the feasibility, functionality, and sustainability of vascularized composite bladder allograft transplantation in treating patients wi…

Neurogenic BladderBladder DysfunctionImmunosuppression

Estimated

~$10 – $6,250

University of Southern CaliforniaNCT05462561

Phase 4

Urinary Microbiome Changes Following Administration of 500 mg of NDS-446 in Women With Dry OAB at 12 Weeks - a Single-center Study

The purpose of this study is to learn about how the use of 500 mg of dried cranberry powder extract (NDS-446) changes the bacteria that normal reside in the bl…

Overactive Bladder

Estimated

~$10 – $6,250

Loyola UniversityNCT05557279

Phase 4

Cognitive, Urinary, and Functional Trajectories of Older Women Using Pharmacologic Treatment Strategies for Urgency Incontinence

The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) bet…

Urinary Incontinence, UrgeUrinary IncontinenceOveractive Bladder+3 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT05362292

Phase 1

Long-term Follow-up Study of Patients Who Received EG110A, a Non-replicative Herpes Simplex Virus 1-derived Gene Therapy Expressing a Transgene Encoding the Light Chain of Botulinum Toxin F

The aim of this study is to continue following participants who have received EG110A during five years to know how it is tolerated in humans, any side-effects …

Urinary Bladder, OveractiveSpinal Cord Injury

Estimated

~$10 – $7,500

EG 427NCT07227285

Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy

The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for w…

Lower Urinary Tract SymptomsStress Urinary IncontinenceUrge Urinary Incontinence+6 more

Estimated

~$10 – $1,125

Hartford HealthCareNCT07175805

Sample Collection for Ongoing Research and Product Evaluation (SCORE) Study

The SCORE study is a prospective, multi-site clinical trial designed to collect blood and tissue samples, along with relevant clinical data, from participants …

Breast CancerLung CancerMuscle Invasive Bladder Cancer+9 more

Estimated

~$10 – $1,050

Natera, Inc.NCT07318051

Phase 1

A Phase 1 Dose-Escalation and Expansion Study of Intratumorally Administered ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas

A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dos…

Triple Negative Breast CancerDiffuse Large B Cell LymphomaFollicular Lymphoma+11 more

Estimated

~$10 – $8,750

OncoNano Medicine, Inc.NCT06022029

Observational

Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation

Electrical stimulation of the sacral nerve can help with bladder problems and pelvic pain but researchers don't understand exactly how the stimulation helps. T…

Overactive Bladder

Estimated

~$10 – $6,250

University of MichiganNCT06983470

Phase 3

Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection

Comparing white-light cystoscopy (WLC) and blue-light cystoscopy (BLC) in TURBT for high risk (HR) non-muscle invasive bladder cancer (NMIBC) patients is cruci…

Bladder Cancer

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT06525571

Observational

Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural Area

The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for…

Polysubstance AddictionOpioid Medication Assisted TreatmentTreatment Adherence+2 more

Estimated

~$10 – $6,250

University of Maryland, College ParkNCT05973838