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A Phase II, Open Label, Multicenter, Single Arm Study of WSD0922-FU for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With First-Line Osimertinib Treatment and Harbor a C797S Mutation

This is a Phase II, Open Label, Multicenter, Single Arm Study of WSD0922-FU for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose D…

Non Small Cell Lung Cancer

Estimated

~$10 – $8,750

Wayshine Biopharm, Inc.NCT06868485

Phase 2

Phase II Study of Adagrasib + Stereotactic Radiosurgery (SRS) for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

This is a single arm phase 2 trial is to evaluate the efficacy of SRS plus adagrasib for the treatment of brain metastases for patients with KRAS G12C-mutated …

Non Small Cell Lung CancerNSCLCKRAS G12C

Estimated

~$10 – $7,500

Ryan Gentzler, MDNCT06248606

Phase 3

GOG-3068: A Phase III Randomized Trial of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) With Cisplatin Versus no HIPEC at the Time of Optimal Interval Cytoreductive Surgery Followed by Niraparib Maintenance in Patients With Homologous Recombinant Deficient (HRD +) Newly Diagnosed Stage III and IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer (Heated Ovarian Treatment Trial)

Patients will be registered prior to, during or at the completion of neoadjuvant chemotherapy given per standard institutional guidelines +/- bevacizumab on Da…

Stage III Ovarian CancerStage IV Ovarian CancerStage III Primary Peritoneal Cancer+3 more

Estimated

~$10 – $6,250

GOG FoundationNCT05659381

Impact of Help-Seeking Behaviors on Allergic Rhinitis, Asthma Control, and Mental Health: A Retrospective and Longitudinal Analysis of Allergy Medication Use

This study explores how help-seeking behaviors for both emotional well-being and allergies impact the management of allergic rhinitis, asthma, and mental healt…

Mental Health ConditionsAllergic

Estimated

~$10 – $1,050

QHSLab, Inc.NCT06623799

A Multi-Center, Prospective Registry to Evaluate the Continued Safety and Performance of the Foot and Ankle Products

The objective of the registry is to evaluate the continued safety and performance of Arthrex foot and ankle products, including the ProStop® implant for hyperp…

Hyperpronated FootReconstruction Surgeries of the FootFixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle+11 more

Evidence-based Sexual and Reproductive Health Intervention Using a Multiphase Optimization Strategy

Floreciendo is a sexual and reproductive health workshop for Latina teens (ages 14-18 years) and their female caregivers (e.g., mothers, sisters, grandmothers)…

Sexual Risk BehaviorSexually Transmitted InfectionsUnplanned Pregnancy

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT06223165

Phase 3

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

The primary aim of this implementation-effectiveness trial is to examine the effectiveness of Mindfulness-Oriented Recovery Enhancement (MORE) and patient-cent…

Chronic PainPrescription Opioid MisuseSubstance-Related Disorders+6 more

Estimated

~$10 – $6,250

University of UtahNCT06387290

Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Breast Cancer

The purpose of this research study is to test a new process for diagnosing breast cancer by examining changes to your DNA that can be detected from a blood tes…

Breast Cancer (Locally Advanced or Metastatic)Healthy Volunteers (HV)Unhealthy Volunteers+1 more

Estimated

~$10 – $750

University of Maryland, BaltimoreNCT07374796

Phase 4

The Effects of Doxycycline on Inflammation and the Microbiome: 'Flipping the Script' on STI PEP

This study is being done to test the effects of doxycycline on inflammation and the bacteria in the body in people with HIV and in people on HIV pre-exposure p…

Sexually Transmitted Infections (STI)

Estimated

~$10 – $6,250

Emory UniversityNCT07215325

Observational

Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures

The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes. The main questi…

TraumaRib FracturesChest Wall Disorder+6 more

Estimated

~$10 – $6,250

Loma Linda UniversityNCT06533904

Observational

Imaging Pain in a Virtual World: Neuroimaging Biomarkers for Assessing Brain Mechanisms Mediating Virtual Reality Pain Management in Children

This study aims to use functional near-infrared spectroscopy (fNIRS) to identify and quantify pain biomarkers during burn dressing changes and pain relief indu…

Acute PainPediatric ALLProcedural Pain+1 more

Estimated

~$10 – $6,250

Nationwide Children's HospitalNCT06303687

Observational

Evaluating Optimal Perioperative Pain Management: A Prospective Randomized Control Trial of Laparoscopic Transversus Abdominis Plane Block With Local Anesthetic, Laparoscopic Transversus Abdominis Plane Block Alone, and Local Anesthetic Alone in Minimally Invasive Oncologic Surgery

This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally inv…

Oncologic SurgeryCancerCancer Surgery+8 more

Estimated

~$10 – $7,500

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)NCT06731998