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1,513 recruiting studies matching your filters

A Multicenter, Randomized, Open-Label, Phase 3 Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab Versus Chemotherapy Plus Trastuzumab Plus or Minus Pembrolizumab as First-Line Treatment in Participants With Unresectable, Locally Advanced or Metastatic HER2-Positive Gastric Or Gastroesophageal Junction (GEJ) Cancer (Destiny-Gastric05)

This clinical trial is designed to assess the efficacy and safety of the triplet combination of trastuzumab deruxtecan (ENHERTU, T-DXd, DS-8201a) plus a fluoro…

Gastric CancerGastroesophageal Junction Cancer

Estimated

~$10 – $7,500

Daiichi SankyoNCT06731478

Phase 2

Phase 2 Trial of 5-Strain Probiotic Formulation in Hormone Receptor-Positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone Loss

This phase II trial tests how well a probiotic, WBF-038, works in preventing bone loss in patients with early-stage hormone receptor-positive breast cancer who…

Anatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8+2 more

Estimated

~$10 – $6,250

Mayo ClinicNCT07044310

Observational

AMD and Validating Rod-Meditated Dark Adaptation With Everyday Task Performance

The goal is to conduct a cross-sectional, single timepoint study on older adults with early and intermediate AMD, and with subretinal drusenoid deposits (SDD),…

Age-Related Macular Degeneration

Estimated

~$10 – $6,250

Duke UniversityNCT06619405

Observational

Development and Evaluation of PPAL Bedside Commode for Safe Independent Toileting Transfers

This research study is being conducted to better understand the impact of the PPAL assisted toileting device. The PPAL consists of a powered, height-adjustable…

Age Problems

Estimated

~$10 – $7,500

Alicia KoontzNCT07221552

Phase 4

Left Sided Stellate Ganglion Blocks Impact on the Rate of Post-operative Atrial Fibrillation in Patients Undergoing Thoracic Surgery: A Pilot Study

The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing es…

EsophagectomyPneumonectomyLobectomy

Estimated

~$10 – $6,250

University of MinnesotaNCT06271707

Phase 3

A Randomized, Double-Blind, Placebo-Controlled, Pivotal Phase 3 Study to Evaluate the Long-Term Efficacy and Safety of Multiple Maintenance Doses of Once Daily Oral Aleniglipron for Chronic Weight Management in Adults With Obesity or Overweight and a Weight-Related Comorbidity

Study GSBR-1290-12 is a Phase 3 pivotal, multicenter, global, randomized, placebo-controlled, double-blind study to investigate the long-term efficacy, safety,…

ObesityOverweightChronic Weight Management

Estimated

~$10 – $8,750

Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure TherapeuticsNCT07654361

Observational

A Prospective, Multi-Center Clinical Study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Patients Requiring Dialysis

A prospective, single-arm, multi-center post-market surveillance study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Pa…

Kidney Disease, End-StageEnd-stage Renal DiseaseArteriovenous Fistula

Estimated

~$10 – $7,500

C. R. BardNCT04634916

Genetic and Environmental Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

The overall objectives of this BETRNet Research Center (RC) are: 1. to conduct a rigorous, integrated spectrum of transdisciplinary human research in Barrett'…

Barrett's EsophagusEsophageal Neoplasm

Estimated

~$10 – $750

Case Western Reserve UniversityNCT00288119

Phase 3

A Phase III Trial of One vs. Two Years of Maintenance Olaparib, With or Without Bevacizumab, in Patients With BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy

This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homol…

Fallopian Tube Endometrioid AdenocarcinomaFallopian Tube High Grade Serous AdenocarcinomaFallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor+9 more

Estimated

~$10 – $7,500

SEntinel Lymph Node Endometrial Cancer Trial: A Prospective Multicenter International Single-Arm Observational Trial (SELECT)

This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a …

Endometrial CancerEndometrioid AdenocarcinomaEndometrial Cancer Stage I

Estimated

~$10 – $750

Memorial Sloan Kettering Cancer CenterNCT04291612

Phase 3

A Phase III Trial Of The Impact Of Sentinel Lymph Node Mapping On Patient Reported Lower Extremity Limb Dysfunction In Endometrial Cancer

This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphed…

Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Estimated

~$10 – $7,500

NRG OncologyNCT05646316

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

The aim is to compare the rate of hypertensive subjects with ICH who reach SBP target with stability within 60 minutes of enrollment, among patients treated wi…

Intracerebral HemorrhageStrokeHypertension

Estimated

~$10 – $1,125

Zeenat Qureshi Stroke InstituteNCT06402968