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The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
The purpose of this study is to determine if the Fractionated Laser Resurfacing (FLR) procedure can protect one forearm/wrist from precancerous actinic keratos…
Effects of Dietary Supplement Intervention on Cognitive Function and Psychological Well-Being
This study's purpose is to evaluate the effects of a dietary supplement on cognitive function and psychological well-being in community-dwelling older adults a…
Alpha Linolenic Acid-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults With Mild Cognitive Impairment: Targeting Cerebrovascular and Blood-brain Barrier Health
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, bl…
Investigating the Role of Follicular Fluid microRNAs in Ovarian Aging and Assisted Reproductive Success
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of i…
Tennessee Alzheimer's Project
The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characte…
A Randomized, Double-blind, Placebo-controlled, Parallel Group, Pilot Study to Evaluate the Effect of a Ketone Ester on Muscle and Immune Function in Older Men and Women Who Are at Risk for Strength and Mobility Decline
This study aims to find out if a food supplement that contains a naturally occurring substance, ketones, can help to improve strength and general wellness in a…
Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults
This study aims to determine the effects of \~12 weeks of repeated hot water immersion ("heat therapy") vs. thermoneutral water immersion on blood pressure and…
Optimization of an Ultrasound Cardiac Guidance Tool
This research examines echocardiography images taken from cardiac patients in relation to the guidance tool developed
SGLT2 Inhibition as a Therapeutic Strategy to Reverse Arterial Stiffening in Aging
Randomized placebo-controlled clinical trial in a cohort of males (n=40) and females (n=40), 60-80 years of age, with the hypothesis that SGLT2 inhibition with…
Walking Speed as a Vital Sign: Enhancing Function in Older Veterans
Walking speed is a powerful predictor of mortality and adverse health consequences (e.g. fall or hospitalization) in older adults. Knowledge of individuals' wa…
Age-specific Neurovascular Effects of Transcranial Photobiomodulation
The goal of this pilot clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared…
Auditory-cognitive Training Paradigm (NIH P01 Project - Speech Perception With High Cognitive Demand)
With advancing age, adults experience increasing speech understanding difficulties in challenging situations. Currently, speech-in-noise difficulties are rehab…