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Prevalence and Care Partner Burden of Individuals With Alzheimer's Disease
This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. T…
Effects of Obesity in the Aged
The overall objective of this application is to investigate the effects of obesity on lung function, exercise tolerance, and DOE in older obese adults as compa…
Effect of Pecan Consumption on Aging
The purpose of this study is to determine if daily consumption of 2 oz of pecans compared to 3.5 oz pretzel snacks for 12 weeks will 1) contribute to the body'…
Innovative Cognitive-Motor Training for Prevention of AD/ADRD
Alzheimer's disease and related dementias (AD/ADRD) greatly affect memory and daily activities in older adults. Mild Cognitive Impairment (MCI) is an early sta…
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation: A Randomized, Controlled Trial
The goal of this randomized, controlled trial is to evaluate the effectiveness of alternative therapies (metformin alone, with rapamycin, and with low-dose nal…
The SickleFit Exercise and Nutrition Randomized Control Trial for Older Adults With Sickle Cell Disease
To goal of this study is to pilot the SickleFit exercise and nutrition intervention in adults with sickle cell disease in a randomized control trial
VITAL-Age Trial (iVS-1 Investigation for Targeting Aging and Longevity)
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplement…
Effects of a 10-day Western Diet on Cardiometabolic and Immune Function in Midlife Adults
This study will implement a Western Diet (WD) to understand cardiometabolic and immune function in middle-aged adults (50- 64 years old). Vascular health, inte…
Comprehensive Cardiac Structure-Function Analysis in Heart Transplantation - Renewal
Heart transplantation (HTx) is a well-established life-saving procedure but is associated with severe complications. Regular monitoring of heart transplant rec…
Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health
Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases,…
Cafe Move: A Novel Program for Prevention of Age-Related Physical Frailty
This project explores a novel means of health promotion and prevention of age-related physical frailty, which is designed to overcome barriers to access and pr…
Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort
To determine whether using bpMRI in subjects who are at high risk of developing prostate cancer in conjunction with PSA will improve prostate cancer screening …