Find your next paid study

National Cancer Institute (NCI)NCT00027274

~$10 – $675

Phase 1

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn, Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells, to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow tr…

Severe Aplastic AnemiaHypo-Plastic MDSMyelodysplastic Syndrome (MDS)

National Heart, Lung, and Blood Institute (NHLBI)NCT03173937

~$10 – $5,625

The Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

Background: Bone marrow failure diseases are rare. Much is known about the diseases at the time of diagnosis, but long-term data about the effects of the dise…

Severe Aplastic AnemiaTelomere Biology DisordersInherited Bone Marrow Failure Syndromes

National Heart, Lung, and Blood Institute (NHLBI)NCT05012111

~$10 – $675

Phase 1

A Pilot Study of Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

This research is being done to investigate the safety and effectiveness of Darzalex Faspro (daratumumab and hyaluronidase-fihj) (a monoclonal antibody that tar…

Hematologic MalignancyBone Marrow Transplant RejectionAcute Myeloid Leukemia (AML)+9 more

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT06398457

Severe Aplastic AnemiaMDS (Myelodysplastic Syndrome)

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells

Background: * Stem cell transplants from related donors (allogenic stem cell transplants) can be used to treat individuals with certain kinds of severe blood …

National Heart, Lung, and Blood Institute (NHLBI)NCT01174108

~$10 – $5,625

Aplastic AnemiaBone Marrow Failure Syndrome

Haploidentical Donor Hematopoietic Cell Transplantation for Patients With Severe Aplastic Anemia

This study is a prospective, single center phase II clinical trial in which patients with Severe Aplastic Anemia (SAA) ) will receive a haploidentical transpla…

St. Jude Children's Research HospitalNCT04558736

Severe Aplastic Anemia (SAA)Hypo-Plastic Myelodysplastic Syndrome (MDS)Paroxysmal Nocturnal Hemoglobinuria (PNH)

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Background: Severe aplastic anemia (SAA), and myelodysplastic syndrome (MDS), and paroxysmal nocturnal hemoglobinuria (PNH) cause serious blood problems. Ste…

National Heart, Lung, and Blood Institute (NHLBI)NCT03520647

~$10 – $5,625

Hematopoietic Cell Transplant and Gene Therapy for Non-Malignant Blood Disorders Biobank Resource (BMT CTN 2402)

A prospective, multicenter study that will establish a repository of biospecimens and clinical data from patients undergoing hematopoietic stem cell transplant…

Aplastic AnemiasHemoglobinopathiesBone Marrow Failure

Medical College of WisconsinNCT07227155

~$10 – $750

Phase 1

A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Dibotatug in Adults With Bone Marrow Failure Syndromes

This is a multicenter, open-label, Phase 1/2 basket study to evaluate the safety and efficacy of Dibotatug (DR-01) in adults with Bone Marrow Failure syndromes.

Bone Marrow Failure SyndromesAplastic AnemiasSevere Aplastic Anemia (SAA)+3 more

Hematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of Platelets+14 more

~$10 – $7,500

Dren BioNCT07712562

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic maligna…

Center for International Blood and Marrow Transplant ResearchNCT01351545

~$10 – $1,125

Hemoglobinopathy (Disorder)Severe Aplastic AnemiaBone Marrow Failure Syndrome

Study of TCR Alpha Beta T-Cell and CD19 B-Cell Depletion for Hematopoietic Cell Transplantation From Haploidentical Donors in the Treatment of Non-Malignant Hematological Disorders in Children

This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is s…

Johns Hopkins All Children's HospitalNCT04356469

Aplastic Anemiade Novo Myelodysplastic SyndromeMyelodysplastic Syndrome+1 more

Phase II Study of Horse Anti-Thymocyte Globulin (hATG), Cyclosporine, Methylprednisolone, and GCSF (Filgrastim or Pegfilgrastim) in Patients With Aplastic Anemia (AA), or Low/Int-1 Risk Myelodysplastic Syndrome (MDS)

This phase II trial studies methylprednisolone, horse anti-thymocyte globulin, cyclosporine, filgrastim, and/or pegfilgrastim or pegfilgrastim biosimilar in tr…