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5 recruiting studies matching your filters

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Muvalaplin on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) Who Have Had a Prior Atherosclerotic Cardiovascular Event or Are at Risk for a First Atherosclerotic Cardiovascular Event

The purpose of this study is to evaluate the efficacy of muvalaplin in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovas…

Elevated Lp(a)Atherosclerotic Cardiovascular Disease (ASCVD)

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07157774

Phase 3

A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Atherosclerotic Cardiovascular Disease (ASCVD), and Elevated LDL-C and Lp(a)

The purpose of the study CTQJ230A12304, is to evaluate the efficacy, safety, and tolerability of pelacarsen (TQJ230) compared to placebo in participants with A…

Atherosclerotic Cardiovascular Disease (ASCVD)

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT06813911

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identif…

Rheumatoid Arthritis (RAAtherosclerotic Cardiovascular Disease (ASCVD)

Estimated

~$10 – $750

Brigham and Women's HospitalNCT07315997

Phase 2

Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD: A Pilot Randomized Open-Label Trial (RESOLVE-CKD Trial)

The overall objective of this pilot randomized clinical trial is to determine whether low-dose Colchicine (LoDoCo) improves vascular disease including vascular…

Chronic Kidney Disease Mineral and Bone DisorderHypertensionDiabetes+3 more

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07654231

Observational

Health Enhanced Artery Risk Tracking With Widespread Implementation and Screening Effort in AtheroSclerotic CardioVascular Disease (HEARTWISE-ASCVD) Study

This multi-site study will test whether an opportunistic AI-based CAC screening and notification intervention can improve cholesterol treatment and lower chole…

Atherosclerotic Cardiovascular Disease (ASCVD)Coronary Artery Calcification

Estimated

~$10 – $6,250

Stanford UniversityNCT07355894