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Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder
The goal of this study is to observe the impact of suvorexant, sold as BELSOMRA, on brain activity of people who frequently use cannabis. Suvorexant is an FDA-…
Refinement and Testing of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
The prevalence of daily cannabis use and Cannabis Use Disorder (CUD) has increased in the United States over the past two decades. Brief, computerized harm red…
Effect of Cannabinoids on Tobacco Product Demand and Pharmacodynamics: Cigarette Use
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of cig…
Talking About Cannabis: Developing an Intervention for Family Members of Young Adults With FEP to Support Reduced Cannabis Use
The objectives of this research is to (1) create a family intervention and provider manual to train family members of young people with psychosis (YP-P) who ar…
Black Adult Resilience Study
Alcohol and cannabis are the most misused psychoactive substances in the United States. The proposed research examines how personally relevant stressful experi…
Effectiveness of Brief Intervention in Primary Care for Diverse Young People
Brief motivational interviewing intervention to address alcohol use among diverse teens 12-17.
Cannabidiol and Cannabis Concentrate Users: A Randomized, Placebo Controlled Study
This study is a randomized, placebo-controlled, dose-ranging trial of plant-derived cannabidiol (CBD) among people who regularly use cannabis concentrates but …
Behavioral Pharmacology of THC and Beta-Myrcene
This study will evaluate the pharmacokinetics and pharmacodynamics of vaporized b-myrcene and THC administered via inhalation.
Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)
Through partnership with Ontracka, the HealthPartners Institute Cancer Research Center created a secure and compliant app-based technology with the ability to …
A Randomized, Placebo Controlled Study of Cannabidiol in Young Adult Cannabis Users
The investigators will study the harm-reducing effect of hemp-derived CBD in non-treatment-seeking emerging adults who use cannabis regularly. The study will u…
Sex Differences in the Interface Between Cannabis Use and Stress Among Emerging Adults
The interface between cannabis use and stress is a particularly important focus for sex differences research in emerging adults. Given the dynamics at play in …
A Phase I Single-Arm Trial to Test the Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use Disorder (CUD)
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms…