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An Intervention to Reduce Discrepancy in Everyday Preferences
Dementia is a disabling, progressive major neurocognitive disorder. Although cognitive symptoms drive the diagnosis of dementia, neuropsychiatric symptoms (NPS…
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
The RAATE proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The stud…
Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot Study
The objective of this project is to test the feasibility of using a smartphone app in a community setting through collaborating with community-based organizati…
Mechanisms of Mindfulness for Cognition in Early-Stage Alzheimer's Disease
The goal of this clinical trial is to learn if mindfulness meditation can improve outcomes in older adults with and without cognitive impairment. The main ques…
Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy
The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such a…
Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid, and Tau in Older Adults (IPAT Study)
The purpose of this study is to determine if intensive lowering of systolic blood pressure (SBP), using FDA approved medications (antihypertensive), reduces Al…
A Pragmatic Trial of the TabCAT Brain Health Assessment for the Detection of Cognitive Impairment in Primary Care
Efficient and user-friendly paradigms to detect cognitive impairment, including dementia are needed in primary care. The TabCAT Brain Health Assessment accurat…
a Randomized, Double Blind, Placebo Controlled Clinical Trial Exploring the Target Engagement and Tolerability of Terazosin Hydrochloride in Patients With Dementia With Lewy Bodies
The TZ-DLB trial will be a 3:2 (active:placebo) randomized, double-blind, placebo-controlled Pilot trial to evaluate the tolerability of terazosin for the trea…
Protocol for Maintaining and Improving Mental Status in Alzheimer's Disease (PROMIS-AD): a Pilot Study of Repetitive Transcranial Magnetic Stimulation of the Precuneus for Alzheimer&Amp;Amp;#39;s Disease
The goal of this clinical trial is to learn if using deep repetitive transcranial magnetic stimulation (rTMS) targeting the precuneus is feasible, tolerable, a…
5-Cog Paradigm to Improve Detection of Cognitive Impairment in Primary Care: Pragmatic Clinical Trial
Cognitive impairment related to dementia is frequently under-diagnosed in primary care settings. This problem is more prevalent in health disparities populatio…
Testing the Pain Clinical Practice Guideline Using the Evidence Integration Triangle
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and include…
Development and Pilot Testing of a Novel Text Messaging Intervention to Improve Emergency Department Care Transitions Among Care Partners of Persons Living With Cognitive Impairment
The purpose of this research study is to develop and test a text-messaging intervention for emergency department (ED) discharge care transitions experienced by…