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2,199 recruiting studies matching your filters

Detection of Colorectal Cancer or Advanced Neoplasia by Stool DNA in Lynch Syndrome: CORAL Study

This study collects blood and stool samples from patients with suspected or diagnosed Lynch syndrome to evaluate a deoxyribonucleic acid (DNA) screening techni…

Colorectal CarcinomaLynch Syndrome

Estimated

~$10 – $750

Mayo ClinicNCT05410977

Phase 2

A Phase II, Open-label, Multicenter, Master Protocol to Evaluate the Safety and Efficacy of Novel Study Interventions and Combinations in Participants With Colorectal Cancer (CANTOR)

The main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC…

Metastatic Colorectal Cancer

Estimated

~$10 – $7,500

AstraZenecaNCT06792695

Microbiome Determinants of Adverse Effects of Stereotactic Radiosurgery

This prospective observational study will investigate the relationship between the gut microbiome and adverse effects following stereotactic radiosurgery (SRS)…

Adverse Radiation EffectsRadiation Necrosis

Estimated

~$10 – $750

University of ChicagoNCT07767981

Phase 1

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

The goal of this clinical trial is to test two investigational COVID-19 booster vaccines, called CoTend-s3BXBB and CoTend-BXBB, in healthy volunteers ages 40-6…

COVID-19SARS-CoV-2 Infection

Transanal Irrigation for the Management of Early Low Anterior Resection Syndrome (LARS): A Pilot Randomized Controlled Trial

Transanal irrigation (TAI) has shown to improve fecal incontinence and increase quality of life in patients with low anterior resection syndrome (LARS). This t…

Colorectal CancerLow Anterior Resection Syndrome

Estimated

~$10 – $6,250

Case Comprehensive Cancer CenterNCT07219745

Phase 4

Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems

The investigators would like to study the differences in the quality of Platelet Rich Plasma (PRP) between two different machines in those with knee osteoarthr…

Knee OsteoarthristisCartilage DamagePlatelet Rich Plasma+1 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07491367

Phase 2

A Phase 2 Study of the Safety and Efficacy of Neoadjuvant Botensilimab in Combination With Balstilimab in the Treatment of Microsatellite Stable / Mismatch Repair Proficient Early Rectal Cancer (RECTIFY-1)

This is a multi-site, prospective, non-randomized phase 2 study evaluating neoadjuvant botensilimab in combination with balstilimab for patients with microsate…

Early Rectal CancerStage I Rectal CancerMicrosatellite Stable Rectal Carcinoma

Estimated

~$10 – $7,500

Dana-Farber Cancer InstituteNCT07735624

Phase 2

A Single Arm Open-Label Pilot Study to Investigate the Safety and Clinical Activity of Cemiplimab, A Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients With Incurable NUT Carcinoma (NC)

This phase II trial studies how well cemiplimab works in treating patients with nuclear protein of testis (NUT) carcinoma for which no treatment is currently a…

Metastatic NUT CarcinomaUnresectable NUT Carcinoma

Estimated

~$10 – $6,250

Northwestern UniversityNCT07050186

Phase 4

Semaglutide for Metabolic and Adiposity-Related Targets in Youth With Autism Spectrum Disorder (SMART-ASD)

This study is a 6-month, two-arm, RCT which will evaluate the effectiveness and safety of semaglutide in adolescents aged 12-18 years with autism spectrum diso…

Autism Spectrum DisorderObesity

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT07770152

Phase 2

A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

A5388 is a phase II, two-arm, randomized, double-blind, placebo-controlled study that will enroll 48 antiretroviral therapy (ART)-naïve adults with acute HIV i…

Acute HIV Infection

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT05719441

Phase 4

A Randomized Controlled Trial Comparing Renal Effects of Vancomycin Combined With Either Piperacillin/Tazobactam or Meropenem: VPT Patient Safety (VPS) Study

The VPT Safety Trial (VPS) compares two common antibiotic combinations to see how they affect the kidneys of patients in the hospital with serious infections. …

InfectionAcute Kidney InjurySepsis

Estimated

~$10 – $7,500

Bassett HealthcareNCT07556107

Observational

Healing Hearts of Hospitalized Patients With Virtual Reality: A Pragmatic, Crossover Trial

The study aims to evaluate the impact of a bedside-delivered virtual reality (VR) mindfulness experience on well-being and psychosocial outcomes among hospital…

Well-Being, PsychologicalAnxietyAffect+1 more

Estimated

~$10 – $6,250

Stanford UniversityNCT06935604