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Optimization of tDCS Brain Network Engagement in Depression
Patients, physicians, and those who fund depression research are keenly interested in depression treatments that do not involve taking medications. One promisi…
Neural and Behavioral Correlates of Live Face-to-Face Interactions
This study aims to understand the neural mechanisms that underlie synchronization of two brains during social interactions.
Mitigating Neural Hypoexcitability and Weakness During Disuse in Women
Clinical trial The goal of this clinical trial is to learn how muscle weakness and atrophy develop during short periods of arm immobilization and whether a typ…
Acceptance and Commitment Therapy for Individuals With MNCD and Their Care Partners: An In-Person and Telehealth Individual Therapy Approach
This project aims to implement and evaluate a dyadic intervention (i.e., acceptance commitment therapy) for persons with AD/ADRD and their care partners. We hy…
Evaluating the Impact of Psychotherapeutic Advertising Claims on Cannabis Purchasing
In the U.S., legal cannabis is frequently advertised as an effective treatment for mental health problems such as anxiety and depression-particularly online. S…
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects
This study seeks to measure the effects of smokeless tobacco product risk messages on sensory experiences and future intentions to use.
A Double-Blind, Placebo-Controlled, Parallel Group, Efficacy and Safety Study of ACP-211 Monotherapy in Adults With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment
The goal of this clinical trial is to learn if ACP-211 can help treat adults with major depressive disorder (MDD) who have not improved with antidepressant the…
Understanding the Mechanisms Driving the Reduction of Repetitive Negative Thought
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health pro…
A Phase 2, Multicenter, Double-blind, Randomized, Placebo-controlled Trial to Assess the Efficacy, Safety, and Tolerability of Repeated Doses of VLS-01 Buccal Film in Participants With Treatment Resistant Depression
This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal…
The Center for Enhancing Triage and Utilization for Depression and Emergent Suicidality (ETUDES) in Pediatric Primary Care-iCHART RCT
This protocol will test the effectiveness of an intervention, iCHART (integrated Care to Help At-Risk Teens) and facilitate recruitment for other studies in th…
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
A prospective, multinational, randomized, double-blind, clinical trial evaluating the safety and effectiveness of a novel atrioventricular interval modulation …
MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial
This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous …