This protocol will investigate whether topical application of N-acetyl cysteine (NAC) eye drops decreases oxidative stress and confers cytoprotection in patien…

Fuchs Endothelial Corneal Dystrophy

~Estimated

~$10 – $7,500

Massachusetts Eye and Ear InfirmaryNCT04440280

Phase 2

A Multicenter, Randomized, Double-Masked, Placebo-Controlled Phase 2 Study of EO2002 in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction (EMERALD)

This study will evaluate the safety and effectiveness of a single injection of EO2002 at one of two dose levels (150,000 or 500,000 magnetic human corneal endo…

Corneal EdemaFuchsFuchs Dystrophy+9 more

A Phase 2, Multicenter, Open-Label Study to Assess the Pharmacodynamics, Safety, and Tolerability of DT-168 Ophthalmic Solution in Patients With Fuchs Endothelial Corneal Dystrophy Undergoing Keratoplasty

The purpose of this study is to evaluate the pharmacodynamics, safety, and tolerability of DT-168 Ophthalmic Solution in pre-keratoplasty patients with Fuchs e…

Fuchs Endothelial Corneal DystrophyFuchs

~Estimated

~$10 – $8,750

Design Therapeutics, Inc.NCT07024693