Find your next paid study

University of FloridaNCT06635811

Phase 1

Studying Human Cognition During Deep Brain Stimulation Surgery Using High-Density Neural Probes and Pharmacological Interventions

This is a research study to determine how COBENFY KarXT (FDA approved), a drug which has been approved for treatment of certain disorders, affects brain activi…

EpilepsyEssential TremorSeizures+6 more

University of Texas Southwestern Medical CenterNCT07721272

Phase 1

Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor

This objective of this study is to document the safety and feasibility of electrical stimulation of the deep cerebellar nuclei for refractory tremor using the …

TremorEssential Tremor

The Cleveland ClinicNCT07049003

Phase 2

A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period to Evaluate the Efficacy and Safety of AGN-151607-DP (USAN: gemibotulinumtoxinA) for the Treatment of Upper Limb Essential Tremor in Adults

Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as…

Upper Limb Essential Tremor

Coordinated Reset Deep Brain Stimulation for Essential Tremor

Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinat…

Essential TremorUpper Extremity Essential Tremor

University of MinnesotaNCT05897775

Phase 1

Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential Tremor

This open-label pilot study will evaluate the safety, tolerability, feasibility, and preliminary efficacy of repeated low-intensity focused ultrasound pulsatio…

University of California, Los AngelesNCT07599592

DystoniaDrug Induced DystoniaParkinson Disease+8 more

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dyst…

Massachusetts Eye and Ear InfirmaryNCT05317390

~$10 – $7,500

Parkinson's Disease (PD)Essential Tremor

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

This study will examine how two important brain circuits - one involving the subthalamic nucleus (STN) and one involving the ventral intermediate nucleus of th…

Boston University Charles River CampusNCT07455760

Parkinson's DiseaseEssential Tremor

Sensory-specific Peripheral Stimulation for Tremor Management

The purpose of this study is to understand the neurophysiological mechanisms of peripheral electrical stimulation (PES) in modulating supraspinal tremorogenic …

Shirley Ryan AbilityLabNCT04501133

~$10 – $7,500

Algorithms for Programming DBS Systems for ET

Deep brain stimulation (DBS) targeting the Vim thalamus (ventralis intermedius nucleus) is an FDA-approved neuromodulation therapy for treating postural and ac…

University of MinnesotaNCT03984643

Directional Versus Nondirectional Deep Brain Stimulation of the VIM Thalamic Nucleus for Essential Tremor: Assessment of Therapeutic Window, Speech, Gait and Balance

This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for…

Oregon Health and Science UniversityNCT04828798

Dual Lead Thalamic DBR-DBS Interface for Closed Loop Control of Severe Essential Tremor

This is a feasibility study based on physician-initiated Investigational Device Exemption (IDE) including intraoperative experiments and chronic testing of imp…