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101 recruiting studies matching your filters

Improving Uroflowmetry Interpretability: Evaluating the Impact of Patient Reminder Systems

The purpose of this study is to evaluate the impact of pre-procedure patient reminder systems on patient satisfaction, preparedness, and anxiety among patients…

Pelvic Organ ProlapseUrinary Incontinence

Estimated

~$10 – $6,250

Ohio State UniversityNCT07692789

Phase 1

Pilot Study of Haploidentical or Matched Donor Virus-Specific T-cells (Cytomegalovirus (CMV) or Adenovirus (AdV)) to Treat CMV or AdV Reactivation or Disease in Patients After Solid Organ or Hematopoietic Stem Cell Transplantation (HCT)

This trial studies the side effects and how well allogeneic cytomegalovirus-specific cytotoxic T lymphocytes (donor cytomegalovirus \[CMV\] specific cytotoxic …

Allogeneic Hematopoietic Stem Cell Transplantation RecipientCytomegalovirusDonor+2 more

Estimated

~$10 – $7,500

Sumithira VasuNCT03665675

Phase 2

A Phase 2, Multicenter, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of ARGX-121 SC in Adult Participants With Primary IgA Nephropathy

The study will assess how ARGX-121 affects immunoglobulin A nephropathy (IgAN) disease outcomes, such as renal function, how it is distributed and eliminated f…

Immunoglobulin A Nephropathy (IgAN)

Estimated

~$10 – $7,500

argenxNCT07773727

A Clinical and Genetic Investigation of Pituitary and Hypothalamic Tumors and Related Disorders

There is a variety of tumors affecting the pituitary gland in childhood; some of these tumors (eg craniopharyngioma) are included among the most common central…

PanhypopituitarismGigantism/AcromegalyProlactinoma+1 more

Estimated

~$10 – $675

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT00001595

Phase 3

A Single-arm, Multicenter, Phase III Study to Assess Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients of 2 to <18 Years of Age With Primary Immunoglobulin A Nephropathy (IgAN)

A Phase III, single-arm, multicenter pediatric clinical study evaluating atrasentan in children and adolescents aged 2 to \<18 years with primary immunoglobuli…

Berger DiseaseBergers DiseaseIgA Nephropathy+3 more

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT07498335

Phase 1

A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

Background: GM1 gangliosidosis is a disorder that destroys nerve cells. It is fatal. There is no treatment. People with GM1 are deficient in a certain enzyme.…

Lysosomal DiseasesGangliosidosisGM1

Estimated

~$10 – $5,625

National Human Genome Research Institute (NHGRI)NCT03952637

Phase 4

A Multicenter, Single Arm, Open Label, Pilot Study to Assess the Effect of Atrasentan Alongside Supportive Care on Structural and Functional Changes in Kidneys of Adult Patients With IgA Nephropathy (IgAN)

This multicenter, single-arm, open-label Phase 4 pilot study evaluates the effects of atrasentan added to optimized supportive care on kidney structure and fun…

IgA Nephropathy (IgAN)Immunoglobulin A Nephropathy (IgAN)

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT07820995

Phase 2

STOMP OUT: A Phase 2 Study To Evaluate The Effects Of Ivonescimab In Patients With Unresectable/Metastatic Adrenocortical Carcinoma (ACC) Or Unresectable Pheochromocytoma/Paraganglioma (PPGL)

To learn if ivonescimab can help to control previously treated, locally advanced or metastatic ACC or PPGL.

Adrenocortical CarcinomaPheochromocytomaParaganglioma

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT07743138

Observational

Minimally Invasive Neuroendoscopic Ultra-Early Targeted ICH Evacuation (MINUTE) Trial

MINUTE is a prospective, multi-center, randomized, controlled, blinded assessor, adaptive enrichment design, clinical trial. Eligible patients with spontaneous…

Basal Ganglia Intracerebral Hemorrhage

Estimated

~$10 – $6,250

Weill Medical College of Cornell UniversityNCT07260916

Phase 4

Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery

Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized …

Pelvic Organ Prolapse (POP)Stress Urinary Incontinence (SUI)Postoperative Pain

Estimated

~$10 – $6,250

University of California, Los AngelesNCT07600697

Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related Disorders

Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations. Affect…

Organic AcidemiaMethylmalonic AcidemiaInborn Errors of Metabolism

Estimated

~$10 – $675

National Human Genome Research Institute (NHGRI)NCT00078078

Immune Monitoring and Assay Development in Organ Transplant Recipients

The purpose of this study to develop a well-characterized library of blood, biopsy tissue, and urine samples from transplant patients. Subjects without transpl…

Organ TransplantationTransplantation Immunology

Estimated

~$10 – $750

Emory UniversityNCT01283295