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Precision-based Teleexercise Trial to Increase Adherence in People With Disabilities
The purpose of this 32-week study is to use an innovative experimental design known as SMART (Sequential Multiple Assignment Randomized Trial), which will allo…
Effects of Pecans on Brain Health in Older Americans With Mild Cognitive Impairment: Gut-brain Axis
This project will investigate whether daily snack consumption can improve memory, mood, and overall brain function in people with cognitive impairment. Sixty p…
Development and Testing of BAJJAJJA: An Intervention to Promote Economic Empowerment and Health of Grandmothers Who Provide Primary Care for Grandchildren in Uganda
Background: There are an estimated 163 million children worldwide who are under the care of their grandparents or other relatives. In Uganda, social determina…
Evaluating Screening Adherence Between Moment for Parents App and Attention Control
Mental health challenges, such as depression and anxiety, are the most common medical complications during pregnancy and after childbirth. Many women experienc…
Addressing Diabetes by Elevating Access to Nutrition: the ADELANTE Study
The goal of ADELANTE is to determine whether a multi-level intervention to improve household food insecurity and glycemic control is effective for Latino patie…
Obtaining Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research
Background: This study is designed to provide samples to help us study the genes your blood cells are making as well as the proteins, sugars, fats, vitamins a…
Identifying the Ideal Dose of Structured Summer Programming for Mitigating Accelerated Summer BMI Gain
Studies show that virtually all increases in children's (5-12yrs) BMI occur during the summer, no matter children's' weight status (i.e., normal weight, overwe…
Evaluating the Effectiveness of a Personalized Therapeutics Clinic (PTC) Intervention on Drug-Drug Interactions (DDIs) and Drug-Gene Interactions (DGIs)
The purpose of this study is to determine whether a consultation with a Personalized Therapeutics Clinic, or PTC, will help participants lower the risk for sid…
Dinner Time for Obesity and Prediabetes
Obesity and its metabolic complications are leading causes of global morbidity and mortality. Evidence is mounting that inappropriate timing of food intake con…
A PHASE 1, OPEN-LABEL, TWO-PERIOD, CROSS-OVER STUDY TO EVALUATE DOSE PROPORTIONALITY OF ATIRMOCICLIB (PF-07220060) PHARMACOKINETICS WHEN ADMINISTERED UNDER FED CONDITIONS TO HEALTHY PARTICIPANTS
The purpose of this clinical trial is to learn about the dose proportionality on the PK of the study medicine (called atirmociclib) when administered in the va…
Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study.
To learn more about how the delivery of medical information affects therapy choices for participants with advanced forms of cancer.
A Single Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IBI3032 in Healthy Participants
This is a randomized, double-blind, placebo-controlled Phase I clinical study evaluating the safety, tolerability, and PK of a single dose of IBI3032 in health…