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22 recruiting studies matching your filters

Multicenter, Randomized, Double-Masked, Placebo-Controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus

Multi-center, parallel-group, placebo-controlled trial designed to assess the safety and efficacy of twice-daily topically administered GLK-221 Ophthalmic Solu…

Keratoconus

Estimated

~$10 – $8,750

Glaukos CorporationNCT07400952

Clinical Trial of OCT-based Scleral Lens Fitting With Wide-Field OCT

The purpose of this study is to see if OCT technology can optimize scleral contact lens fittings. Subjects with keratoconus, post-penetrating keratoplasty (PK)…

KeratoconusIrregular; Contour of Cornea

Estimated

~$10 – $750

Oregon Health and Science UniversityNCT04570020

Phase 1

A Dose Ranging, Multicenter, Sham-Controlled Study to Evaluate the Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus

Clinical Trial to Evaluate the Safety and Efficacy of Corneal Cross-linking in Subjects with Keratoconus.

Progressive Keratoconus

Estimated

~$10 – $8,750

Glaukos CorporationNCT05314738

Exploring Enrollment and Engagement Trends in Individuals Managing Keratoconus: A Comprehensive Examination of Data on Keratoconus Clinical Trials

This study aims to investigate the influences behind patient choices regarding involvement, discontinuation, or re-engagement in keratoconus clinical trials. U…

Keratoconus

Estimated

~$10 – $1,050

Power Life Sciences Inc.NCT06288737

The K-Map Study, Global Prevalence of KC

Keratoconus is a ocular disease classified under ectatic diseases which often results in bilateral and asymmetrical corneal distortion. It usually affects pati…

Keratoconus

Estimated

~$10 – $750

University Hospital, GenevaNCT03115710

Phase 2

Safety and Effectiveness of the PXL -Platinum 330 System for Cornea Collagen Crosslinking in Eyes With Corneal Thinning Conditions

This study study is to determine the effectiveness of cornea cross linking in patients with Keratoconus or other cornea thinning conditions.

Keratoconus

Estimated

~$10 – $7,500

Cohen Laser and Vision CenterNCT05516004

Observational

INTACS® Prescription Inserts Used to Treat Patients With Keratoconus as a Humanitarian Use Device

The US food and Drug Administration (FDA) originally approved INTACS prescription inserts in April 1999 for the correction of low levels of nearsightedness (-1…

Keratoconus

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT02138669

Neuroplasticity of Pain Pathways and Corneal Afferent Regeneration Following Corneal Crosslinking (CXL) in Keratoconus

Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI …

Pain, PostoperativePain, ChronicPain, Acute+5 more

Estimated

~$10 – $750

Boston Children's HospitalNCT04439552

Phase 2

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia

To evaluate the safety and effectiveness of the PXL Platinum 330 system for performing corneal cross-linking (CXL) for the treatment of ectatic disorders.

KeratoconusPellucid Marginal Corneal DegenerationCorneal Ectasia

Estimated

~$10 – $7,500

Goodman Eye CenterNCT04094090

Phase 1

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Conditions

To determine whether the Peschke PXL-330 system is safe and effective in the treatment of corneal thinning conditions.

Keratoconus, UnstableBacterial KeratitisEctasia of Cornea

Estimated

~$10 – $7,500

Pacific Clear Vision InstituteNCT03918408