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Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension
Obesity is a global health concern that is associated with high blood pressure and an increased risk for developing cardiovascular disease. The purpose of this…
Observational Study of Patients Being Treated With Anti-obesity Medication
The goal of this observational study is to learn about the real-world effects of selected obesity medications in adults undergoing medical weight management. T…
Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on methacholine challeng…
A Multi-site, Prospective Registry of Patients Undergoing Gastric Fundal Mucosal Ablation at True You Weight Loss
The purpose of this study is to construct a multi-site, prospective registry to evaluate the clinical outcomes of patients who have undergone gastric fundus mu…
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder - OBOE-Mayo
The goal of this clinical trial is to identify the specific characteristics (phenotypes) that may be useful to help select the right medication for weight loss…
Water Intake and Weight Control in Older Adults
This study is a randomized controlled intervention trial in adults aged 50+ years with overweight or obesity, which will compare three groups with different di…
Diabetes and Heart Disease Risk in Blacks
It is unknown if obesity contributes to the development of heart disease in African American men and women. This study was created to determine whether there …
Using Real-Time Data Capture to Examine Implicit Attitudes as Mediators of Physical Activity Adherence in Interventions
This early-phase trial will test intervention strategies to influence implicit attitudes towards physical activity and determine whether changes in those mecha…
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity: A Pilot Study
The purpose of this study is to determine the effect of tirzepatide on vasomotor symptoms and on measures of biological aging.
Early Tracking of Childhood Health Determinants Study
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mo…
Adaptive Mechanisms Responsible for Weight Change in Youth With Obesity
In this study, doctors want to find out more about why people who lose weight often regain the weight that they have lost once they resume a regular diet and w…
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in ch…