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Water Intake and Weight Control in Older Adults
This study is a randomized controlled intervention trial in adults aged 50+ years with overweight or obesity, which will compare three groups with different di…
Using Real-Time Data Capture to Examine Implicit Attitudes as Mediators of Physical Activity Adherence in Interventions
This early-phase trial will test intervention strategies to influence implicit attitudes towards physical activity and determine whether changes in those mecha…
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in ch…
Metabotyping of a Functional Food, Broccoli Microgreen, in Obese Breast Cancer Survivors
Obesity can pose significant challenges to maintaining long-term health in cancer survivors by increasing their risk of cancer coming back. Eating a healthy di…
Impact of Circadian Misalignment on Energy Balance Regulation
Preliminary findings from the investigators' lab suggest that circadian misalignment, occurring when meals and sleep are mistimed from one another, alters rest…
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental h…
Interscalene vs Phrenic-sparing Blocks in Obesity: Effect of Pre-operative Maximum Inspiratory Pressure in a Randomized Trial
The goal of this clinical trial is to learn whether a phrenic-sparing nerve block can lower early breathing problems after shoulder surgery in adults with obes…
A Randomized, Placebo Controlled and Double-blinded Study Assessing the Safety, Tolerability, Pharmacokinetics, and Efficacy of Subcutaneous Administrations of NNC0174 1213 in Male Participants With Overweight or Obesity.
This study is testing a new study medicine to treat people living with overweight or obesity. The aim of this study is to see if the medicine is safe, how it w…
Pharmacogenetics of Response to GLP1R Agonists
Overweight/obese otherwise healthy volunteers will be recruited from the Old Order Amish population in Lancaster County, PA. Lancaster County, PA. Pharmacodyna…
Resistance Training Modulation of Fat Metabolism in Obese Postmenopausal Women
Adipose tissue turnover plays a critical role in body weight maintenance, and obesity is underscored by the dysregulated balance between fat breakdown and synt…
Efficacy Trial of Healthy Together "Juntos": A Family-based Digital Lifestyle Intervention for Hispanic Adolescents and Their Parents
The purpose of this study is to assess the efficacy of a family-based digital (web and mobile phone-based) program known as Healthy Together ("Juntos") in prev…
Endoscopic Sleeve Gastroplasty (ESG) as a Treatment Option for Obesity in Ulcerative Colitis (UC) Patients Undergoing Colectomy With Ileal Pouch Anal Anastomosis (IPAA)
The purpose of this research is to gather information on the safety and effectiveness of Endoscopic Sleeve Gastroplasty (ESG) for weight loss in a population o…