Find your next paid study

University of North Carolina, Chapel HillNCT07095361

Phase 2

Evaluating the Efficacy and Safety of Saline Irrigation as an Add-On Therapy for Retained Pleural Infections (LYTICS +)

The purpose of this protocol is to conduct a pilot prospective non-blind clinical trial to evaluate the efficacy and safety of a novel saline irrigation techni…

Pleural Effusion Associated With Pulmonary InfectionPleural Effusion DisorderPleural Effusions

Beth Israel Deaconess Medical CenterNCT06713382

Pleural Effusion Disorder

A Pilot Assessment of the Safety and Efficacy of Pleural Irrigation for Retained Pleural Infection Using a Novel Irrigation Device

Single-arm pilot trial of the use of intrapleural saline irrigation to treat retained pleural infections for patients with contraindications to standard of car…

Beth Israel Deaconess Medical CenterNCT06727578

Phase 1

Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease: A Phase I Trial

This research study aims to evaluate the safety and effectiveness of a novel immunotherapy, Fast TIL, an Adoptive Cellular Therapeutic (ACT), to fight cancer t…

Malignant Pleural EffusionMalignant MesotheliomaPleural Effusion, Malignant+1 more

David Bartlett, MDNCT07192900

~$10 – $7,500

Phase 1

Phase I Intra-patient Dose Escalation Study of the IL-6 Receptor Antagonist Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Pleural Effusion or Peritoneal Ascites Due to Metastatic Cancer

The purpose of this study to find out if tocilizumab can be safely infused into chest or abdominal cavities of patients with malignancy ascites (MA) or maligna…

Malignant Pleural EffusionMalignant Ascites

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)NCT06016179

~$10 – $7,500

Phase 1

Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors: A Phase I Trial (FAST TILS 2)

This research study aims to evaluate the safety and effectiveness of a novel immunotherapy, Fast TIL, an Adoptive Cellular Therapeutic (ACT), to fight cancer t…

Malignant Pleural EffusionMalignant MesotheliomaPleural Effusion, Malignant+1 more

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)NCT07443020

~$10 – $7,500

Pulmonary EdemaPneumoniaAtelectasis+11 more

Clinical Utility of Portable Dynamic Chest X-Ray (DDR) in the ICU: Clinical Trial to Demonstrate the Feasibility of Deploying DDR Technology in the ICU - A Study to Prove Its Increased Diagnostic Value

Dynamic digital radiography (DDR) is a new advanced version of chest radiography that captures dynamic images at a rate of 15 frames per second. It is coupled …

Brigham and Women's HospitalNCT06538376

Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions

This is a randomized control trial of patients with suspected malignant pleural effusions to compare whether patients who have a thoracentesis or pleuroscopy (…

Pleural EffusionCancer

Icahn School of Medicine at Mount SinaiNCT06892691

University of North Carolina Pleural Fluid Registry

Research with biospecimens such as blood, tissue, or body fluids can help researchers understand how the human body works. Researchers can make new tests to fi…

Lung CancerLung InfectionBreast Cancer+2 more

UNC Lineberger Comprehensive Cancer CenterNCT05620329

~$10 – $750

Congestive Heart Failure(CHF)Pleural Effusion Due to Congestive Heart Failure

Role of Therapeutic Thoracentesis in Hospitalized Patients With Acute Decompensated Heart Failure: Randomized Controlled Trial

The goal of this study is to assess if removal of fluid around the lungs (pleural effusion) by a routine procedure called as thoracentesis is helpful to decrea…