Find your next paid study

Abramson Cancer Center at Penn MedicineNCT07832630

Severe Aplastic AnemiaMDS (Myelodysplastic Syndrome)

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells

Background: * Stem cell transplants from related donors (allogenic stem cell transplants) can be used to treat individuals with certain kinds of severe blood …

National Heart, Lung, and Blood Institute (NHLBI)NCT01174108

~$10 – $5,625

Observational

Preservation of Beta Cell Function in Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions…

Diabetes Mellitus, Type 2Impaired Glucose Tolerance (IGT)Impaired Fasting Glucose (IFG)

The University of Texas Health Science Center at San AntonioNCT02969798

Phase 1

An Open-label, Multi-center, Phase I/II Study to Assess Safety, Tolerability and Efficacy of DFT383 in Pediatric Participants With Nephropathic Cystinosis, Followed by a Long-term Extension Phase

An open-label, multi-center, phase I/II study to assess the safety, tolerability and efficacy of DFT383 in pediatric participants with nephropathic cystinosis,…

Nephropathic Cystinosis

Novartis PharmaceuticalsNCT06910813

Phase 1

RAdiation comBined With BIspecific T-Cell Engager in DLL3 Expressing Tumors (RABBIT) Study: A Phase I/II Study of AMG757 / Tarlatamab and Concurrent Radiation Therapy in Tumors With High Prevalence of DLL3

Phase I study to examine safety of the addition of concurrent tarlatamab with standard palliative and consolidative RT regimens , with a main cohort of N=20-24…

MelanomaMedullary Thyroid CancerSinonasal Undifferentiated Carcinoma+8 more

University of ArizonaNCT06814496

Observational

Clinical Performance Evaluation of Two Monthly Replacement Silicone Hydrogel Multifocal Toric Lens Designs in Habitual Soft Contact Lens Wearers

To compare the performance of two leading soft multifocal Toric contact lenses.

AstigmatismMyopia

CooperVision International Limited (CVIL)NCT07829419

Parkinson's Disease (PD)Deep Brain Stimulation

An Open-label Clinical Trial Investigating the Long-term Safety of Buntanetap in Treating Participants With Parkinson's Disease

This study will examine the long-term safety of buntanetap in participants with PD. This will be a 36-month open-label safety study. This study will be conduct…

Annovis Bio Inc.NCT07284784

Langerhans Cell Histiocytosis (LCH)Juvenile Xanthogranuloma (JXG)Rosai-Dorfman Disease (RDD)+1 more

A Phase II Trial of the MEK Inhibitor Mirdametinib in Histiocytic Disorders

The purpose of this study is to see if treatment with mirdametinib in patients with Langerhans cell histiocytosis (LCH) or other histiocytic disorders will be …

Children's Hospital Medical Center, CincinnatiNCT06153173

~$10 – $5,625

Hemophagocytic Lymphohistiocytoses

Frontline Ruxolitinib With De-Intensified HLH-94 for Adult Hemophagocytic Lymphohistiocytosis (HLH): A Multicenter, Single-Arm Phase 2 Study

This phase II trial tests the effects of ruxolitinib in combination with a de-intensified HLH-94 drug regimen has on patients with newly diagnosed hemophagocyt…

Jerry Lee, MD, MSc, MPhilNCT06160791

~$10 – $7,500

Phase 1

A Phase 1, Randomized, Double-blind, Placebo-controlled, Dose Escalation Study Evaluating Safety and Pharmacokinetics of VX-581 in Healthy Subjects

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of single dose of VX-581 and multiple ascending doses of VX-581 alone a…

Cystic Fibrosis

Vertex Pharmaceuticals IncorporatedNCT07283770

Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I)

Phase II open label study designed to evaluate the efficacy and safety of P-Sam in patients with aggressive, solid, NOTCH mutant or p63 low (B7-H4 high) R/M AC…

Adenoid Cystic Carcinoma

M.D. Anderson Cancer CenterNCT07162480

Observational

A Medical Nutrition Supplement for Cystic Fibrosis

The goal of this study is to learn if one nutrition supplement formula works better than a different formula in adults with cystic fibrosis. The main question …

Cystic Fibrosis (CF)