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1,369 recruiting studies matching your filters

A Phase 1 Study of GRN163L (Imetelstat) in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia That is in Second or Greater Relapse or That is Refractory to Relapse Therapy; Myelodysplastic Syndrome or Juvenile Myelomonocytic Leukemia in First or Greater Relapse or is Refractory to Relapse Therapy

This phase I trial tests the safety, side effects, and best dose of imetelstat in combination with fludarabine and cytarabine in treating patients with acute m…

Recurrent Childhood Acute Myeloid LeukemiaRecurrent Childhood Myelodysplastic SyndromeRecurrent Juvenile Myelomonocytic Leukemia+3 more

Estimated

~$10 – $7,500

Children's Oncology GroupNCT06247787

Observational

The Worksite Heart Health Improvement Project + Function Focused Care (WHHIP+FFC) Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities

The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcome…

Worksite Health PromotionLifestyle Risk ReductionOccupational Burnout+4 more

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT07785947

Phase 1

Phase I Trial of Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Background: Non-Hodgkin lymphoma (NHL) is the most common cancer among people living with HIV in the United States. People with HIV are up to 17 times more li…

Diffuse Large Cell LymphomaNon-Hodgkin LymphomaBurkitt Lymphoma+2 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05389423

Phase 2

Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT)

This phase II trial studies how well combination chemotherapy works in treating patients with newly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT…

Anaplastic Kidney Wilms TumorRecurrent Kidney Wilms TumorStage II Kidney Wilms Tumor+2 more

Estimated

~$10 – $7,500

Children's Oncology GroupNCT04322318

Phase 2

Phase II Investigator Sponsored Study of CPX-351 in Combination With Ivosidenib for Patients With IDH1 Mutated Acute Myeloid Leukemia or High-Risk MDS

This phase II trial investigates how well CPX-351 and ivosidenib work in treating patients with acute myeloid leukemia or high-risk myelodysplastic syndrome th…

Acute Myeloid Leukemia With Gene MutationsMyelodysplastic SyndromeMyeloproliferative Neoplasm+2 more

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT04493164

Phase 2

Dose-response of Aerobic Training During Chemotherapy for Gastrointestinal Cancers

The purpose of this study is to find the level of aerobic exercise (AT) that is practical, is safe, and has positive effects on the body that may reduce the si…

Gastrointestinal Cancer

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05789485

Observational

DRAIN-HF: Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failur…

Heart FailureCardiorenal SyndromeCardio-Renal Syndrome+5 more

Estimated

~$10 – $7,500

ProcyrionNCT05677100

Chronic Health Conditions in Down Syndrome-Associated Acute Leukemia: The Down Syndrome Phenotyping Acute Leukemia Study in Survivors (DS-PALS Survivors)

This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increas…

B Acute Lymphoblastic Leukemia Associated With Down SyndromeDown SyndromeMyeloid Leukemia Associated With Down Syndrome

Estimated

~$10 – $1,125

Children's Oncology GroupNCT05702645

Phase 1

Pediatric Acute Leukemia (PedAL) Screening Trial - Developing New Therapies for Relapsed Leukemias

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials…

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Myeloid Leukemia Post Cytotoxic Therapy+5 more

Estimated

~$10 – $8,750

PedAL BCU, LLCNCT04726241

Phase 3

A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is r…

Childhood Extracranial Germ Cell TumorExtragonadal Embryonal CarcinomaGerm Cell Tumor+27 more

Phase 3

A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (IND#:133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy and immunotherapy (chemo-immunotherapy) for patients with High-…

B Acute Lymphoblastic LeukemiaB Lymphoblastic LymphomaCentral Nervous System Leukemia+2 more

Estimated

~$10 – $7,500

Children's Oncology GroupNCT03959085

Changes in Postprandial Hormone Levels in Cystic Fibrosis Related Diabetes.

In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates …

Cystic Fibrosis

Estimated

~$10 – $675

University of CincinnatiNCT06163482