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A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea
Studies show that sleep apnea increases the risk of cardiovascular disease and is associated with obesity. However, it is unclear how sleep apnea affects fat t…
Effect of Whole Food Plant-based Diet in Patients With Obstructive Sleep Apnea
This research aims to develop a better understanding and clinical knowledge of the effects of a plant based diet on severity and daytime sleepiness in Obstruct…
Effectiveness of Interocclusal Aligner (IOA) on Preventing Occlusal Changes in Patients Treated With a Mandibular Advancement Device (MAD): A Preliminary Study
This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Devi…
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)
The overall objective of this randomized clinical trial is to test the effectiveness of a personalized approach to the surgical treatment of OSA in children wi…
An App-Based, Precision Medicine Approach to Optimize Long-Term CPAP Adherence and Quality of Life
The purpose of this study is to optimize the time of CPAP usage to at least 6 hours a night for 6 nights per week for people who have OSA with the help of a sm…
Multicenter Pilot Study of the Cryosa System for the Treatment of Obstructive Sleep Apnea
This is a prospective, multicenter, non-randomized single-arm safety and performance study to collect data to evaluate the safety of the Cryosa procedure to tr…
Endotypic Traits and Obstructive Sleep Apnea Surgery
This study will examine factors associated with outcomes after soft palate surgery and medications (acetazolamide, eszopiclone) that may treat other potential …
MicroRNAs as Biomarkers for Obstructive Sleep Apnea
Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project wi…
Safety and Effectiveness of Slow Wave Device for the Treatment of Obstructive Sleep Apnea
This is a safety and efficacy trial for a Slow Wave, Inc. UASD oral appliance for the treatment of Obstructive Sleep Apnea. This trial will recruit 60-80 parti…
A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Post-Operative Steroids After Sleep Surgery
The primary objective of this randomized, placebo-controlled, double-blind study will be to determine if postoperative steroids significantly improve subjects'…
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea
Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgi…
The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)
Major progress has been made in the area of cardiovascular disease, but we believe that further progress will involve mechanistically addressing underlying res…