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9 recruiting studies matching your filters

Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)

The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduc…

PPAPSpine Fusion

Estimated

~$10 – $7,500

Senthil SadhasivamNCT05367609

Phase 4

Pharmacokinetics and Impact of Magnesium Sulfate on Neuromonitoring in Spinal Surgery

Intraoperative neurophysiologic monitoring (IONM) is commonly used during complex spinal surgery to monitor the integrity of neural structures and improve the …

SpinePainSpine Surgery+3 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06975072

Observational

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic c…

Spinal FusionHyperglycemiaPostoperative Pain Management+9 more

Estimated

~$10 – $7,500

Alexander T. YahandaNCT07218133

Observational

A Prospective, Randomized, Multi-center Study to Assess the Performance of MagnEtOs Flex Matrix Mixed With Local Autograft Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented poSterolatEral Lumbar/Thoraco-lumbar Fusion (PLF)

This is a phase IV post-marketing study for MagnetOs Flex Matrix. MagnetOs Flex Matrix is a synthetic bone graft extender product that is routinely used by sur…

Degenerative Disc DiseaseSpine FusionLeg Pain and/or Back Pain

Estimated

~$10 – $8,750

Kuros Biosurgery AGNCT05037968

Phase 3

Effect of Ketamine on Intraoperative Motor Evoked Potentials

The goal of this clinical trial is to learn about the effect of ketamine on intraoperative motor evoked potentials in adult patients undergoing thoracolumbar s…

Spine FusionSpine TumorSpinal Stenosis

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06140927

Phase 4

Comparing Multifidus Cervicis Plane Block Vs. Sham Block, In Reducing Postoperative Pain And Opioid Consumption In Patients Undergoing Elective Primary Posterior Cervical Spine Fusion Surgery

The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sha…

Cervical Spine Fusion

Estimated

~$10 – $6,250

Hartford HospitalNCT05996133

Phase 4

The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion: A Randomized Control Trial

The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.

Spine FusionLumbar Spine DegenerationPain, Postoperative+1 more

Estimated

~$10 – $6,250

University of Southern CaliforniaNCT05746143

Observational

A Prospective, Randomized, Multi-Center Study to Assess the Safety and Performance of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers (DBX or Grafton) Mixed With Local Autograft in Patients Undergoing One to Two-Level Instrumented Posterolateral Lumbar/Thoracolumbar Fusion (PLF)

This is a phase IV post-marketing study for MagnetOs Easypack Putty. MagnetOs Easypack Putty is a synthetic bone graft extender product that is routinely used …

Degenerative Disc DiseaseSpine FusionBack Pain

Estimated

~$10 – $8,750

Kuros Biosurgery AGNCT04679844

Phase 4

Postoperative Steroids and Recovery After Spine Fusion

This trial studies how well low-dose postoperative corticosteroids (FDA approved) affect patient outcomes (patient reported outcomes, pain medication use, leng…

Spine Fusion

Estimated

~$10 – $6,250

Oregon Health and Science UniversityNCT04568837