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Neural Control of Gait & Navigation in ADRD, Aim 3 Clinical Trial
Brain network segregation, or independent functioning, declines with age and is associated with slower walking speed. Here, the investigators will determine th…
Motivating Activity Through Text - Comparing Human and AI Messages (MATCH AIM) Trial
The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to…
Effects of Lactate on Brain Carbohydrate Metabolism in Healthy Aging
The brain's primary source of fuel is glucose. Unfortunately, the brain's ability to use glucose declines during normal aging. This decline in brain glucose me…
Beta3-adrenergic Receptors and Cardiovascular Function in Aging Women
To determine if vascular beta3 adrenergic receptors are present and functional in aging women and can be targeted to attenuate sympathetic vasoconstriction and…
Evaluation of C-arm Photon Counting Detector Cone Beam CT (PCD-CBCT) for Image-Guided Interventions
The overarching objective of the project is to develop a new C-arm interventional x-ray imaging platform that integrates both a photon counting detector and a …
A Single Arm, Multicenter, Prospective, Open Label, Longitudinal Phase 3 Study of Prostate Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) Combined With Magnetic Resonance Imaging (MRI) Compared to Standard of Care (SOC) for the Detection of Prostate Cancer (PCa).
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resona…
Personalized Memory Enhancement in Aging: Pattern-Optimized tACS With Closed-Loop Precision Modulation
This project optimizes high-resolution transcranial Alternating Current Stimulation (tACS) to improve memory in healthy older adults, advancing drug-free appro…
Strength and Pain-Coping Through Resilience and Knowledge
Older adults who are 50 years of age and older with depressive symptoms, pain and difficulty with mobility will participate in the SPARK intervention study tha…
Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and Mild Cognitive Impairment
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in an aging population.
Comparison Between Eccentric Hamstring Strength Training and Sprint-Specific Training on Muscle Hypertrophy, Strength, Power, and Sprint Performance in Club Sport Collegiate Athletes
The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with th…
A Multi-center, Post-market Cosmetic Evaluation of Ariessence™ Pure PDGF+ Following Ablative Laser for the Tolerability and Improvement in the Appearance of Aging Skin.
ariessence is intended to be used as a viscous, leave-on solution designed for topical application to the face. It is intended to be used following non-medical…
Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subject…