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Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional Factors (Extension)
This project extends the investigators' previous research regarding the intersecting risks of alcohol, sexual risk behavior (SRB), and sexual aggression (SA) i…
StuDy AimED at Increasing AlCohol AbsTinEnce (DEDICATE)
The goal of this clinical trial is to test the feasibility \& acceptability of an integrated CM-PST intervention (in K99 phase) and preliminary efficacy (in R0…
Randomized Controlled Trial of the Thrive Person-Centered Planning Program for Young Adults With FASD
This study evaluates the Thrive person centered planning program for young adults with fetal alcohol spectrum disorders. Participants are randomized to either …
Selective Glucocorticoid Receptor Antagonism in Alcohol Use Disorder: A Human Laboratory Study
The goal of this study is to learn if PT150 can reduce the behavioral and physical effects of stress, alcohol, and alcohol use in people with alcohol use disor…
Phase I, Dose-Escalation Study of Dihydromyricetin (DHM) to Treat Alcohol-Associated Liver Disease
The current proposal is designed as a first-in-human Phase 1 open-label, dose-escalation study to assess the safety, pharmacokinetics, and the maximum tolerate…
Enhancing Prospective Thinking in Early Recovery
The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use diso…
A Prospective Multicenter International Randomized Controlled Trial Comparing Surgical and Medical Therapies in the Treatment of Advanced Metabolic Dysfunction Associated Steatohepatitis
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), a major global public health con…
The Impact of Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment
This human laboratory study will use cognitive, behavioral, and subjective measures to characterize impairment associated with co-use of alcohol and vaporized …
A Focus on Alpha-1 Blockade as a Novel Pharmacological Treatment for AUD
The goal of this research is to replicate findings previously conducted in a pilot trial and to understand, mechanistically, the role of stress in the developm…
CHOICES-TEEN: Efficacy of a Bundled Risk Reduction Intervention for Juvenile Justice Females
This randomized controlled trial will: 1) Test the efficacy of the CHOICES-TEEN (CT) intervention compared with an Attentional Control (AC) condition on reduci…
Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder
Alcohol Use Disorders are currently positioned as the third leading cause of preventable death in the United States, constituting a humanitarian crisis with su…
Preventing Alcohol Use Disorders and Alcohol-Related Harms in Pacific Islander Young Adults
This study will: (1) refine and finalize the SPEAR intervention manual for preventing alcohol use disorders (AUD) and associated harms for Pacific Islander you…