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Automated Reinforcement Management Systems, Phase II
The Automated Reinforcement Management Systems Phase II (ARMS II) study is a phase II trial is a randomized controlled, non-medicated assisted trial to determi…
Alcohol Research Consortium in HIV: Relapse Prevention Arm
3-arm type 1 pilot implementation-efficacy trial for people with alcohol use disorders to examine the preliminary effectiveness and feasibility of an adapted 2…
Tirzepatide for the Treatment of Alcohol Use Disorder: A Pilot Randomized Controlled Trial
This is a pilot, 4-week, double-blind, placebo-controlled, randomized trial of individuals with alcohol use disorder (AUD) to receive weekly injections of eith…
Investigation of Cerebellar Involvement in AUD
The goal of this observational and interventional study is to better understand the involvement of the cerebellum in the brain reward system in persons with al…
Human Laboratory Study of Apremilast for Alcohol Use Disorder
Primary: The primary objective of this study is to compare the efficacy of two different maintenance doses of apremilast (tablets) in reducing alcohol craving …
Designing Deaf-MET: A Deaf-Accessible Pre-Treatment for Alcohol Use Disorder
This pilot study will evaluate the feasibility, acceptability, and preliminary efficacy of an adaptation of Motivational Enhancement Therapy (MET) titled "Deaf…
Feasibility and Acceptability of a Novel Implementation Intervention to Promote Alcohol Use Disorder Treatment in Hepatology Clinics
The goal of this project is to improve provision of integrated medications for alcohol use disorder (MAUD) with brief counseling for patients with alcohol use …
Developing and Evaluating a Positive Valence Treatment for Alcohol Use Disorder With Anxiety or Depression
The proposed study consists of two phases. During Phase 1, the investigators will recruit a small sample of participants to complete a psychosocial interventio…
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder: A Double-Blind, Dose-Comparison Concurrent Control Randomized Trial
This study aims to determine the safety and preliminary efficacy of psilocybin-assisted psychotherapy in improving alcohol-related outcomes among adults with s…
Transcranial Alternating Current Stimulation to Boost the Efficacy of Motivational Interviewing
The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during m…
A Double-masked, Randomized, Phase II Study to Compare the Effectiveness of 20mg Oral Suvorexant (SUV) Versus Placebo (1:1) in Participants With Co-occurring Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD)
This study is to determine if suvorexant (SUV) will reduce insomnia in 76 men and women veteran and non-veterans between the ages 21-65 with posttraumatic stre…
Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study
The goal of this clinical trial is to determine whether Emotional Brain Training (EBT), a behavioral modification method, can help manage stress and health pro…