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8 recruiting studies matching your filters

Adverse Outcomes and Mortality in Liver Transplant

Prospective natural history pilot study to explore the link between muscle composition using an MRI-based Muscle Assessment Score (MAsS) and adverse outcomes i…

End Stage Liver DIseaseSarcopeniaSarcopenic Obesity+1 more

Estimated

~$10 – $6,250

Mayo ClinicNCT05477277

Functional Assessment in Liver Transplant Candidates (FrAILT) Study

This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disabili…

End Stage Liver Disease

Estimated

~$10 – $675

University of California, San FranciscoNCT03228290

Observational

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

This study utilizes a web-based application to help patients on the organ transplant waitlist communicate patient's need for a living donor via social media an…

End Stage Renal DiseaseEnd Stage Liver Disease

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT03803423

Phase 2

A Phase 2a, Open Label, Dose Escalation Study for Safety, Tolerability, and Efficacy of Hepatocyte Transplantation Into Periduodenal Lymph Nodes Among Subjects With End-Stage Liver Disease

This Phase 2a clinical trial is a dose escalation study of the safety, tolerability, and efficacy of hepatocyte transplantation into lymph nodes via endoscopic…

End Stage Liver Disease

Estimated

~$10 – $8,750

LyGenesis, Inc.NCT04496479

Phase 1

A 12-Month, Open-Label Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Siplizumab as Induction Therapy in Patients With Autoimmune Liver Diseases Undergoing Liver Transplantation (SET-SAIL)

There is a significant unmet need for safe and effective therapeutic approaches to prevent immune-mediated graft injury and its complications in liver transpla…

Autoimmune Liver DiseaseLiver Transplant DisorderAutoimmune Hepatitis+3 more

Estimated

~$10 – $7,500

Elizabeth C. VernaNCT06455280

Observational

HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease

This research study is evaluating a program that entails a healthcare at home intervention for people with advanced liver disease.

CirrhosisEnd Stage Liver DIseaseLiver Cirrhosis+1 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05205954

Phase 1

A Phase I Feasibility Study of HSPC Infusion Following Total Lymphoid Irradiation and Anti-thymocyte Globulin in Patients With a Pre-existing, Well-functioning HLA-matched Living-donor Liver Transplant to Induce Immune Tolerance.

This clinical trial is being conducted to help liver transplant recipients safely discontinue toxic immunosuppressive drugs years after surgery. Lifelong use o…

Liver TransplantationImmune ToleranceImmune Tolerance/Drug Effects+6 more

Estimated

~$10 – $6,250

University of California, Los AngelesNCT07269041

Observational

LiverPAL: A Randomized Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (A…

Liver Disease ChronicEnd Stage Liver DIseaseCirrhosis+2 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05998330