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27 recruiting studies matching your filters
Short-term Effects of Methamphetamine on Residual Latent HIV Disease (EMRLHD) Study
The most commonly used illicit stimulant in people with HIV (PWH) is methamphetamine (MA). Prior studies demonstrate strong evidence that MA promotes increased…
Psilocybin Recovery Intervention for Stopping Methamphetamine Use
The goal of this clinical trial is to learn whether it is possible to use psilocybin in combination with motivational support therapy to treat moderate-to-seve…
The Low-Down on Methamphetamine Isomers: Prevalence and Pharmacology in Humans
This study is being done to understand the metabolism and impairment profile of methamphetamine (meth). Meth exists as two chemical structures that are mirror …
An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder Using fMRI to Identify Novel Neural Biomarkers
This open label pilot study will assess the feasibility and preliminary efficacy of tirzepatide which will be prescribed under its FDA approved weight manageme…
A Phase 2 Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants With Methamphetamine Use Disorder Not Seeking Treatment Receiving a Single Dose of Methamphetamine
The purpose of the study is to evaluate the safety, efficacy, and pharmacokinetics of four single, increasing doses of CS-1103, given by intravenous (IV) infus…
Glutide for Ending Methamphetamine
GEM is a two-phase study to evaluate the use of semaglutide (Wegovy) for the treatment of methamphetamine use disorder (MeUD). The first phase is a pilot stud…
Advancing Troiluzole as a Treatment for Methamphetamine Use Disorder: A Human Laboratory Study
This will be a human laboratory study evaluating the influence of troriluzole treatment on the effects of methamphetamine. Supported by and included in the Hel…
Advancing Non-Abstinence Outcomes in the Treatment of Methamphetamine Use Disorder
Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral c…
PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use d…
Cue Reactivity Modulation in MSM With Methamphetamine Use Disorder
In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation…
Optimizing HIV Prevention for Highly Vulnerable Methamphetamine-using Sexual Minority Men
This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI…
Modulating Explore-exploit Biases by Improving Mood in Adults With Methamphetamine Use Disorder
In this project, the investigators examine behavior and associated brain activity during explore-exploit decision-making tasks performed pre- and post-modulati…