Find your next paid study

University of Missouri-ColumbiaNCT07478172

Multiple SclerosisSpasticity

The Effectiveness of Dry Needling on Reducing Spasticity and Promoting Mobility and Balance in People With Multiple Sclerosis

The investigators are doing this study to see if a treatment called dry needling improves muscle spasticity (muscle tightness) in people who have Multiple Scle…

University of Kansas Medical CenterNCT06394310

Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.

Spastic Diplegia

The University of Texas Health Science Center, HoustonNCT02535936

Spinal Cord InjuryAmbulation DifficultyMuscle Spasticity

Exoskeleton and Spinal Cord Stimulation for SCI

The overall aim of this project is to assess the effect of combining transcutaneous lumbosacral stimulation (TLS) during Exoskeleton Assisted Walking (EAW) com…

Kessler FoundationNCT03096197

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biolog…

Hereditary Spastic ParaplegiaSPG47SPG50+8 more

Boston Children's HospitalNCT04712812

~$10 – $750

Cerebral PalsySpastic Cerebral Palsy

Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy

12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times/week. All clinical and physiological assessments col…

Burke Medical Research InstituteNCT05571033

~$10 – $7,500

Phase 3

Intrathecal Administration of MELPIDA (AAV9/AP4M1) For Hereditary Spastic Paraplegia Type 50 (SPG50): A Phase 3, Open-Label Trial With Matched Prospective Concurrent Control Arm

Phase 3, open-label study to assess the efficacy and safety of a single lumbar intrathecal administration of MELPIDA in individuals with Hereditary Spastic Par…

Hereditary Spastic Paraplegia Type 50

Elpida Therapeutics SPCNCT06692712

~$10 – $8,750

Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, …

Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more

Investigating the Genetic Basis of Hereditary Spastic Paraplegia

The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders. The HSP…

Hereditary Spastic ParaplegiaNeurodegenerative DiseasesPediatric Disorder+3 more

Boston Children's HospitalNCT05354622

~$10 – $750

Functional and Neurodevelopmental Outcomes Following Intensive Multimodal Neurorehabilitation in Pediatric Patients With Neurodevelopmental Disorders, Including Chromosomal Abnormalities

This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitati…

Neurodevelopmental DisordersNeurodevelopmental Disorders (NDD)Neurodevelopmental Disorders and Developmental Abnormalities+20 more

Spinal Cord InjurySpasticityShockwave Therapy

~$10 – $1,125

Phase 1

Pilot Trial of a Novel, Non-invasive Treatment for Upper-limb Spasticity in People With Spinal Cord Injury

Approximately 305,000 people live with a spinal cord injury (SCI) in the United States. Sixty percent of these individuals have tetraplegia, which can cause si…

Kessler FoundationNCT07501429

Spasticity as Sequela of StrokeSpastic Cerebral PalsySpasticity, Muscle

A Randomized, Sham Controlled Trial of Dorsal Root Rhizotomy Stereotactic Radiosurgery Versus Standard of Care for Spasticity Associated With Stroke, Spinal Cord Injury & Cerebral Palsy

A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurge…