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Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Corn
The purpose of this research study is to identify biomarkers of whole grain (WG) corn intake following an acute exposure in a pharmacokinetic (how the body abs…
Evaluation of [11C]ZTP-1 to Image PDE4B
Background: PDE4B is a protein in cells that helps turn off certain chemical signals after they ve done their job. It controls inflammation, immune responses,…
Discovering Determinants of Food Intake by Application of Machine Learning to Complex, High-Dimensional Data
Background: Many people in the United States are overweight or obese. Researchers want to learn why some people can overeat and not gain weight, whereas other…
Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies
Objective: To screen and create a list of adult volunteers in good health for participation in research studies conducted at the National Institutes of Health …
Prevalence Effects in Visual Search: Theoretical and Practical Implications (J)
The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tas…
PET Imaging of Noradrenergic Transmission in the Brain
Background: Researchers have developed a new radioactive tracer (11C-ARMI). A tracer is a drug that attaches itself to other chemicals in the body and lights …
Strengthening Bonds: A Telephone Reminiscence Intervention to Reduce Social Isolation and Improve Mental Health in Rural Older Adults
The goal of this study is to learn whether a telephone-based program that helps people share life memories can reduce loneliness and improve mental well-being,…
Impact of Physiologic Pacemaker Programming on Cognitive Function and Health Status in Patients With Symptomatic Bradycardia
This proof-of-concept study will evaluate whether physiologic pacemaker programming improves cognitive function and health status in patients with symptomatic …
Normative Values in Audiovestibular Testing
Background: \- Researchers at the National Institutes of Health give many tests of hearing and balance. These tests can help detect problems that affect heari…
An Open-label, Single-sequence Multiple Cohort Study to Assess the Effect of Multiple Doses of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on the Pharmacokinetics of Single Doses of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity
This study will measure the effects of multiple doses of AZD6234, AZD9550 and a combination of AZD9550 and AZD6234 given as injection(s) on pharmacokinetics (P…
A Repository to Study Host-Microbiome Interactions in Health and Disease
Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers …
Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder
Many people with depression do not get better with standard treatments like medications or talk therapy. Transcranial magnetic stimulation (TMS) is a non-invas…