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70 recruiting studies matching your filters

Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease - UNMC/Medtronic Collaborative Acute Feasibility Pilot

This is an open-label, non-randomized, proof-of-concept comparison of clinical vs. research stimulation patterns in patients with Parkinson's disease (PD) bein…

Parkinson's Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of NebraskaNCT04799470

Phase 3

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early-Stage Parkinson's Disease

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of prasinezumab compared with placebo in participants with early-stage…

Parkinson's Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Hoffmann-La RocheNCT07174310

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

The objectives of this study are to collect the long-term safety and effectiveness data of performing thalamotomy for tremor dominant Parkinson's Disease (TDPD…

Tremor Associated With Tremor Dominant Parkinson's Disease

Estimated

~$10 – $1,125

Actual pay is set by the research site.

InSightecNCT04991831

Phase 1

An Investigator-initiated Clinical Trial of Safety and Efficacy of Transplantation of Human Induced Pluripotent Stem Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)

To evaluate the safety and efficacy of transplantation of human induced pluripotent stem cell-derived dopaminergic progenitors, CT1-DAP001, into the corpus str…

PD - Parkinson's Disease

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of California, San DiegoNCT06482268

Observational

Sensing in Sleep and Deep Brain Stimulation

Participants in this study have Parkinson's Disease and already have a device, called the Percept RC Deep Brain Stimulation device implanted. People with Parki…

Parkinson's Disease and ParkinsonismDyssomnia

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Health Science Center at San AntonioNCT07636720

Observational

A Feasibility and Efficacy Study of a Breathwork and Meditation Intervention (SKY Breath) on the Psychophysiological Well-Being of Individuals With Parkinson's Disease (iPD) and Their Care Partners

The goal of this feasibility study and clinical trial is to learn if an evidenced-based breathwork and meditation intervention (SKY Breath) will improve the me…

Parkinson's Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Nova Southeastern UniversityNCT06581523

Phase 2

Neural Mechanisms Underlying the Benefits of Aerobic Exercise in Advanced Parkinson's Disease

This study is focused on people with Parkinson's disease who already have deep brain stimulation devices. The goal is to understand how aerobic exercise, speci…

Parkinson's DiseaseDeep Brain Stimulation

Estimated

~$75 – $2,000

Actual pay is set by the research site.

The Cleveland ClinicNCT07442747

Phase 2

Interventional, Randomized, Double-blind, Parallel-group, Placebo-controlled, Flexible-dose Trial of Lu AF28996 in Adults With Parkinson's Disease Experiencing Motor Fluctuations

This trial will evaluate the effects of Lu AF28996 in adults with Parkinson's disease (PD) experiencing motor fluctuations despite optimized non-invasive sympt…

Parkinson's Disease

Estimated

~$75 – $3,000

Actual pay is set by the research site.

H. Lundbeck A/SNCT07514858

Observational

Quantitative Digitography to Evaluate the Efficacy of Image Guided Algorithmic DBS Programming

The goal of this clinical trial is to evaluate an automated deep brain stimulation (DBS) algorithm developed by Boston Scientific called Illumina 3D for motor …

Parkinson's Disease (PD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT07215481

Observational

A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

The purpose of this research study is to examine the effects of a 3-month personalized community-based walking program using a digital music-based device desig…

Parkinson's Disease (PD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston University Charles River CampusNCT07705373